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Table 2 Table showing sensitivity increase of peptide identifications with updated filters and precursor charge estimation.

From: Increasing peptide identifications and decreasing search times for ETD spectra by pre-processing and calculation of parent precursor charge

OMSSA Search

True positives (1% FDR)

Improvement

Original Filters

2118

--

New Precursor Filter

2326

9.8%

New Precursor and Noise Filters

2423

14.4%

Precursor Charge Determination Algorithm

2516

18.8%

(3.5 times faster)

  1. This table shows the number of true positives (TP) at 1% FDR for various stages of spectral processing and precursor charge assignment. A column showing percent increase (over OMSSA with original filters and range search option) in peptide identifications for each method is also provided.
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