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Figure 1 | Proteome Science

Figure 1

From: Proteomic profiling for the identification of serum diagnostic biomarkers for abdominal and thoracic aortic aneurysms

Figure 1

Venn diagrams showing the number of proteins with differential levels in postsurgical sera compared with those in presurgical sera of patients with AAA and TAA. (A) Number of proteins that were identified in at least one sample among 7 samples in each group. (B) Number of proteins that were identified in at least 6 samples among 7 samples in each group. (C) Number of remaining proteins after exclusion of proteins for which iTRAQ ratios at the second time point (T2) to those at the first time point (T1) showed ≧ 1.3 fold or < 0.77 fold in at least two samples in 4 control sera (T2 vs. T1). (D) Numbers of proteins with significantly increased (≧ 1.3 fold, postsurgical vs. presurgical) and decreased level ratios (< 0.77 fold, postsurgical vs. presurgical) that were identified in at least 6 samples among 7 samples in sera of AAA and TAA patients and with statistical significant levels of iTRAQ ratio of postsurgical/presugical of patients’ sera compared with that of T2/T1 volunteers’ sera (p < 0.05, patient vs. control).

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