Table 2 List of differentially-expressed proteins between control and p110γ knockdown cells after 5 Min IGF-I stimulation determined by DIGE and identified by MS a
Name | Accession | MW (kDA)/pI | Spot No. | Fold change | Mascot search results | ||
|---|---|---|---|---|---|---|---|
ID/Total queries | Sequence coverage (%) | Combined IonScore | |||||
Eukaryoticelongation factor 2 | eEF2_HUMAN | 96.2/6.4 | 100 | 1.4 | 22/545 | 18 | 395 |
101 | 1.3 | 14/547 | 16 | 215 | |||
106 | 1.3 | 10/534 | 9 | 137 | |||
Pyruvate kinase isozyme M1/M2 | KPYM_HUMAN | 58.5/8.0 | 265 | 1.3 | 45/462 | 41 | 882 |
267 | 1.3 | 52/560 | 47 | 1112 | |||
275 | 1.3 | 78/572 | 69 | 1471 | |||
Alpha-enolase | ENOA_HUMAN | 47.5/7.0 | 449 | 1.2 | 27/481 | 45 | 556 |
Phosphoglycerate kinase 1 | PGK1_HUMAN | 45.0/8.3 | 542 | 1.2 | 17/519 | 34 | 387 |
L-lactate dehydrogenase A chain | LDHA_HUMAN | 37.0/8.4 | 734 | 1.4 | 11/603 | 23 | 185 |
746 | 1.4 | 8/507 | 15 | 112 | |||
Purine nucleoside phosphorylase | PNPH_HUMAN | 32.3/6.4 | 837 | −1.3 | 3/585 | 9 | 63 |