Figure 5
From: Ranking and compacting binding segments of protein families using aligned pattern clusters
Ten resulting APCs representing the proximal and distal binding segments of the cytochrome c are compared to the HMM logo from pFam. In the largest APC, Cys17 is identified as one of the conserved aligned columns, where His18 binds to the heme iron. In the second largest APC, Met62 is identified as one of the conserved aligned column of the distal binding segment, where Met62 binds the heme iron.