Protein name | Ascension number (Swissprot)/matched 2D coordinates | MW/pI | Peptides (% cov) | Relative change vs normal | Zoomed in gel image showing representative spots | |||
---|---|---|---|---|---|---|---|---|
Abbreviation | (World-2DPAGE portal) | |||||||
 |  | Theory | Experimental |  |  | Normal | Cancer | |
Structural | ||||||||
20 | Stathmin (Phosphoprotein p19) | P16949 /SPOT 2D-001YH8 | 17.3/5.76 | >15.0/5.7 | 4 (18%) | +1.6 |
|
|
STMN1 | ||||||||
1 | Tropomyosin alpha-3 chain (Tropomyosin-3) | P06753 / | 32.8/4.68 | >30.0/4.6 | 6 (13%) | -1.5 |
|
|
SPOT 2D-001EM1 | ||||||||
SPOT 2D-001YBH | ||||||||
TPM3 | SPOT 2D-001JNO | |||||||
4 | Myosin regulatory light chain-2 | P19105 / | 19.8/4.67 | >15.0/4.60 | 5 (17%) | -1.9 |
|
|
SPOT 2D-001JUH | ||||||||
ML12A | SPOT 2D-001JUS | |||||||
Enzymes | ||||||||
6 | Lactoylglutathione lyase (Glyoxalase I). (EC 4.4.1.5) | Q04760 / | 20.8/5.12 | >20.0/5.00 | 10 (22%) | +7.7 |
|
|
LGUL | n/a | |||||||
24 | Triosephosphate isomerase (EC 5.3.1.1) | P60174 / | 26.7/6.45 | >25.0/6.5 | 5 (28%) | +2.5 |
|
|
TPIS | SPOT 2D-0003MP | |||||||
18 | Nucleoside diphosphate kinase A (EC 2.7.4.6) | P15531 / | 17.1/5.83 | >15.0/5.8 | 8 (31%) | +1.5 |
|
|
NDKA | n/a | |||||||
21 | Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) | P61088 / | 17.1/6.13 | >15.0/5.9 | 6 (23%) | +2.6 |
|
|
UBE2N | n/a | |||||||
16 | Gamma-glutamylcyclotransferase (EC 2.3.2.4) | O75223 / | 21.0/5.07 | >20.0/5.0 | 3 (27%) | +2.5 |
|
|
GGCT | n/a | |||||||
14 | Peroxiredoxin-4 (EC 1.11.1.15) | Q13162 / | 30.5/5.86 | >30.0/5.8 | 6 (16%) | +2.2 |
|
|
PRDX4 | n/a | |||||||
19 | Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) | P00441 / | 15.9/5.70 | >15.0/5.70 | 5 (24%) | +1.4 |
|
|
SPOT 2D-001F1V | ||||||||
SODC | SPOT 2D-000ZXR | |||||||
17 | Glutathione S-transferase P (GST class-pi). (EC 2.5.1.18) | P09211 / | 23.3/5.43 | >25/5.6 | 8 (22%) | +1.4 |
|
|
SPOT 2D-001EUM | ||||||||
SPOT 2D-0003Q9 | ||||||||
GSTP1 | SPOT 2D-00085X | |||||||
11 | Proteasome subunit beta type 4 precursor. (EC 3.4.25.1) | P28070 / | 29.2/5.72 | 29.0/5.7 | 6 (15%) | +1.6 |
|
|
SPOT 2D-000851 | ||||||||
PSB4 | SPOT 2D-000D4M | |||||||
Regulatory proteins | ||||||||
3 | 14-3-3 protein beta/alpha | P31946 / | 28.0/4.70 | >25.0/4.50 | 6 (4%) | +1.8 |
|
|
1433B | n/a | |||||||
12 | Prohibitin | P35232 / | 29.8/5.57 | >25.0/5.60 | 5 (12%) | +1.6 |
|
|
PHB | SPOT 2D-001EOL | |||||||
13 | Proteasome activator complex subunit 1 | Q06323 / | 28.7/5.78 | >25.0/5.70 | 2 (4%) | -1.7 |
|
|
PSME1 | SPOT 2D-001YC7 | |||||||
16 | Proteasome activator complex subunit 2 | Q9UL46 / | 27.3/5.44 | >30.0/5.4 | 4 (11%) | -2.3 |
|
|
PSME2 | n/a | |||||||
2 | 14-3-3 protein sigma (Stratifin) | P31947 / | 27.8/4.68 | >25.0/4.50 | 9 (24%) | -2.0 |
|
|
1433S | SPOT 2D-001EP6 | |||||||
22 | Stress-induced-phosphoprotein 1 | P31948 / | 62.6/6.4 | >55.0/6.50 | 11 (12%) | +2.1 |
|
|
STIP1 | n/a | |||||||
10 | Interleukin-1 receptor antagonist protein precursor | P18510 / | 20.0/5.83 | >20.0/5.3 | 2 (8%) | +1.3 |
|
|
IL1RA | n/a | |||||||
5 | Rho GDP-dissociation inhibitor 1 | P52565 / | 23.2/5.02 | 30.0/5.0 | 4 (14%) | +2.6 |
|
|
GDIR | n/a | |||||||
9 | Ran-specific GTPase-activating protein | P43487 / | 23.3/5.19 | 30/5.2 | 5 (18%) | +1.8 |
|
|
RANG | n/a | |||||||
Chaperones | ||||||||
15 | Heat-shock protein beta-1 | P04792 / | 22.8/6.00 | >20.0/5.8 | 11 (32%) | +3.1 |
|
|
SPOT 2D-001JQI | ||||||||
HSPB1 | SPOT 2D-001JQP | |||||||
23 | T-complex protein 1 subunit zeta-2 | Q92526 / | 57.7/6.63 | >55.0/6.8 | 2 (2%) | -1.6 |
|
|
TCPW | n/a | |||||||
Others | ||||||||
8 | Chloride intracellular channel protein 1 (membrane associated) | O00299 / | 26.9/5.09 | >30.0/5.1 | 14 (46%) | -1.7 |
|
|
 | CLIC1 | SPOT 2D-001YBL |  |  |  |  |  |  |