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Table 1 Intensities of protein peaks between patients with HCC and controls

From: Detection and identification of NAP-2 as a biomarker in hepatitis B-related hepatocellular carcinoma by proteomic approach

M/Z

p value

HCC patients

Controls

Expression of biomarkers

  

Mean

SD

Mean

SD

 

4177.021

0

2.4109626

1.7831004

17.790127

12.3304

↓

4284.793

1E-10

4.1675763

2.8210263

18.165137

10.96188

↓

3157.338

2E-10

2.8711763

2.3671242

16.269795

12.3949

↓

2210.294

4E-10

1.2477808

1.4009605

4.5723959

1.643278

↓

3976.459

8E-10

2.6239766

3.4075661

10.778571

7.532834

↓

2931.897

7.6E-09

3.1186882

2.0358896

11.507879

7.729

↓

3954.075

1.11E-08

1.6472851

1.2559403

7.6936686

5.96494

↓

7789.876

3.13E-08

21.662616

9.007951

8.8290885

6.779427

↑

3190.271

3.9E-08

3.5195939

3.2358447

12.027547

8.698558

↓

2880.784

7.45E-08

1.102611

1.3353521

5.001807

4.339702

↓

2042.81

8.59E-08

5.2251662

4.7882565

15.394446

8.244651

↓

4300.805

1.14E-07

6.3052246

2.8188831

14.24708

6.619937

↓

2684.091

3.21E-07

3.262482

3.6567613

9.551285

5.764105

↓

9312.108

3.21E-07

15.704431

4.4922866

8.8978734

4.287706

↑

3272.949

8.18E-07

1.8316758

1.3430214

6.5194098

5.123064

↓

8168.558

2.15E-06

4.2784744

1.7546221

2.2906521

1.328373

↑

7984.144

1.12E-05

6.0715178

4.4504467

2.9324679

1.787027

↑

2233.538

2.99E-05

1.9147055

1.5778554

4.0521515

2.028355

↓

2188.991

3.54E-05

2.5010757

1.5294086

4.3043581

1.881263

↓

2135.285

4.42E-05

3.6300916

3.49041

10.966854

9.955057

↓

11713.42

4.67E-05

4.1459834

5.4995663

1.336294

3.257604

↑

2053.145

5.5E-05

9.7060752

5.9603503

4.3023177

2.231138

↑

11803.06

5.5E-05

1.6426482

1.3296893

0.7800243

0.476692

↑

11913.52

6.47E-05

1.3968035

1.0639529

0.6868796

0.606584

↑

7577.259

8.47E-05

6.5419175

6.7324834

2.9342635

2.346913

↑

3328.797

9.93E-05

4.2466182

2.9569092

6.2898423

2.27614

↓

2458.656

0.00011

5.1397003

9.6317988

12.275455

14.48544

↓

2175.988

0.000116

2.7234278

1.2771298

4.1339189

2.387265

↓

2760.934

0.000338

4.6648972

3.2035945

9.3423629

6.483809

↓

2226.912

0.000452

2.355006

1.6168492

3.8420929

1.696412

↓

3042.037

0.000575

2.0878758

1.5066385

3.9896521

2.661699

↓

3315.627

0.000602

9.5689729

4.8592784

15.151073

7.432231

↓

2025.722

0.000694

4.6839614

3.8381819

1.7500306

1.539545

↑

2798.165

0.000694

2.0897574

2.4307372

3.9262301

3.225462

↓

3142.417

0.000875

3.1393877

1.8539336

6.0137931

4.371349

↓

3497.766

0.001004

1.9353972

2.3046427

4.1676774

3.520588

↑

2604.949

0.001258

1.6948706

2.4206924

3.5161364

2.838326

↓

2635.516

0.001316

1.8316855

2.6597455

3.412366

2.418701

↓

1986.694

0.001503

3.9645947

2.1700129

6.1885737

2.961989

↓

11546.56

0.001503

2.247573

3.0491879

0.6758139

1.142265

↑

5811.636

0.00204

6.4141252

7.5516614

2.3012091

1.338683

↑

10292.36

0.002223

1.8987997

1.2501286

1.0377238

0.735765

↑

4118.351

0.003676

7.11073

5.1441046

11.680701

6.853008

↓

3264.446

0.00668

6.9932534

5.2366332

11.0494

7.096711

↓

2149.367

0.006943

3.7005272

3.7552454

5.9585474

5.335906

↓

2011.105

0.007497

2.6144135

2.0116598

4.2731103

2.674531

↓

2785.17

0.007497

2.5972155

2.4631704

4.4992097

3.047729

↓

3472.829

0.00906

3.1882635

3.4294237

4.5476185

2.91472

↓

5482.928

0.011735

4.8059806

2.9804352

3.4096367

2.533875

↑

3923.203

0.01217

2.4220346

2.3048585

4.3790796

3.64184

↓

2316.308

0.017976

3.4762243

3.7179706

1.6393136

1.780269

↑

6845.999

0.01926

4.9948325

2.3817092

6.838496

3.161917

↓

2692.421

0.019931

4.921541

2.7549713

3.457848

2.217777

↑

3104.495

0.019931

1.3934316

1.4045028

2.3921117

1.843127

↓

2753.121

0.021336

4.4069341

3.9525245

6.3553599

4.472233

↓

3509.35

0.02207

4.5393277

3.3610221

7.2480107

5.319909

↓

6203.673

0.02207

3.3648117

1.6676335

4.5994989

2.159071

↓

9212.971

0.024405

43.945799

32.384871

24.707158

29.86224

↑

4137.329

0.026951

5.4829547

2.9809693

7.0825919

2.943026

↓

9421.615

0.032739

8.5502217

5.7753764

6.0635598

6.172742

↑

5318.755

0.037162

5.2174103

6.0996661

10.364681

11.18352

↓

2953.161

0.039559

9.7117587

7.368618

12.899569

8.162569

↓

4599.027

0.040805

18.449161

16.04898

13.034537

17.97882

↑

7988.252

0.042085

6.4870797

3.9637198

5.3343441

4.792026

↑

4858.969

0.049004

4.0595446

4.2862607

5.63334

4.377429

↓

  1. ↑:Protein peak intensity that was upregulated in the serum of HCC patient.
  2. ↓ : Protein peak intensity that was downregulated in the serum of HCC patient