Figure 13From: Dramatic down-regulation of oxidoreductases in human hepatocellular carcinoma hepG2 cells: proteomics and gene ontology unveiling new frontiers in cancer enzymology _Oxidoreductase enzyme 10-formyltetrahydrofolate Dehydrogenase (FDH; EC:1.5.1.6), removes formyl group from 10-formyltetrahydrofolate (10-formyl-THF). 10-formyl-THF is a critically needed precursor for two reactions of de novo biosynthesis of purine nucleotides.Back to article page