From: Differential chromatin proteomics of the MMS-induced DNA damage response in yeast
Protein name | Enrichment factor | Estimated copies/cell a | Cellular Localization b | Description c |
---|---|---|---|---|
Arp3 | +1.74 | 6650 | Cytoskeleton, Nucleus [54] | Actin-related protein 3, actin filament organization |
Arp4 | +4.20 | 1070 | Nucleus | Actin-related protein 4, chromatin remodeling |
Arp7 | +2.53 | 1360 | Nucleus | Actin-related protein 7, chromatin remodeling |
Arp9 | +3.35 | 1790 | Nucleusd | Actin-related protein 9, chromatin remodeling |
Asc1 | +2.88 | 333000 | Cytoplasm | G protein beta subunit, Small subunit ribosomal protein |
Atp2 | +1.43 | 164000 | Mitochondrion | F1-ATPase beta chain, mitochondrial ATP synthesis |
Cdc10 | +3.09 | 14100 | Septin ring, cytosketelon, nucleusd | Septin ring protein, cell division |
Cgi121 | +3.37 | N.D. | Nucleus [27] | Component of KEOPS, telomere uncapping and elongation |
Crn1 | +4.06 | 2900 | Contractile ring, Cytoskeletond | Coronin, actin filament organization |
Cys3 | +1.65 | 38300 | Cytoplasm | Gamma-cystathionase, Cysteine biosynthesis |
Egd2 | +1.55 | 38000 | Cytoplasm, Nucleus [55] | Component of NAC, ribosome associated |
End3 | +10.4 | 2600 | Cytoskeleton | EH domain protein, actin cytoskeletal organization |
Gdi1 | +1.58 | 7280 | Cytoplasm | GDP dissociation inhibitor, vesicle mediated transport |
Ilv2 | +13.4 | 31900 | Mitochondrion | Acetolactate synthase, amino acid synthesis |
Ilv5 | +1.95 | 883000 | Nucleus, Mitochondriond | Acetohydroxy-acid isomerase, amino acid synthesis |
Lat1 | +2.42 | 5440 | Mitochondrion | Dihydrolipoamide acetyl-transferase, pyruvate metabolism |
Lsp1 | +5.54 | 104000 | Cytoplasm (punctate composite) | Component of eisosome, endocytosis |
Pdb1 | +3.93 | 9970 | Mitochrondrion, Nucleoidd | Pyruvate dehydrogenase, pyruvate metabolism |
Pil1 | +1.65, Pil1(a) +2.31, Pil1(b) | 115000 | Cytoplasm (punctate composite) | Component of eisosome, endocytosis |
Pst2 | +3.37 | 2330 | Mitochondrion, Nucleus [56] | Flavodoxin-like protein |
Qcr2 | +1.73 | 35700 | Mitochondrion | Ubiquinol cytochrome C reductase, respiration |
Raf1 | +3.37 | N.D. | Nucleus [57] | FLP1recombinase activating factor, plasmid maintenance |
Rpb3 | +3.38 | 10000 | Nucleus | DNA directed RNA polymerase II |
Rpc40 | +3.98 | 13000 | Nucleus | Component of RNA polymerases I |
Rpt1 | +1.92 | 105 | Nucleus | ATPase subunit of proteosome |
Rvb2 | +4.03 | 3030 | Nucleusd | Transcription, chromatin remodeling |
Stm1 | +2.21 | 46800 | Cytoplasm, Nucleusd | TOR signaling, telomere structure |
Swi3 | +6.85 | 3150 | Nucleus | Chromatin remodeling complex, SWI/SNF |
Taf14 | +4.32 | 3120 | Nucleus | Subunit of TFIID, TFIIF, INO80, SWI/SNF, NUA3 complexes, chromatin remodeling |
Tfc7 | +3.89 | 2660 | Cytoplasm, Nucleus | RNA polymerase IIIc |
Tub2 | +3.73 | N.D. | Nucleus, Cytoskeletond | Tublin 2, microtubule component |
Ume1 | +2.22 | 3040 | Cytoplasm, Nucleus | Negative regulator of meosis, binding to histone deacetylase RPD3. |
Ura7 | +3.73 | 57600 | Cytoplasm | CTP synthase, phospholipid biosynthesis |