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Table 2 Statistical data for MMS-induced differentially expressed proteins in chromatin fraction.

From: Differential chromatin proteomics of the MMS-induced DNA damage response in yeast

Protein name

DF

p-value

(DF)

EF (+MMS)

p-value

(EF, +MMS)

EF (-MMS)

p-value

(EF, -MMS)

Acf2

+1.48

0.020

+1.57

0.011

-1.30

0.048

Aim13

+1.70

0.0053

+3.30

0.034

+2.27

0.00097

Arp3

+1.35

0.024

N/A

N/A

+1.52

0.063

Atp2

+1.52

0.0093

+1.50

0.093

+5.74

0.000041

Bmh1 (a)

+1.92

0.0014

+3.57

0.0039

-1.03

0.070

Cdc10 (a)

+1.61

0.0034

+7.28

0.0099

+6.33

0.000015

Cdc10 (b)

+1.38

0.044

+1.50

0.18

+2.43

0.0015

Cps1

+1.61

0.010

+2.16

0.0036

-2.57

0.00018

Crn1

+1.78

0.0034

+3.85

0.0024

+2.36

0.0012

Gcv3

+1.75

0.019

+1.07

0.52

-1.90

0.00087

Ilv2

+2.15

0.013

+1.50

0.39

-1.15

0.086

Lsp1 (a)

+1.51

0.0023

+3.17

0.0011

+1.79

0.022

Lsp1 (b)

+1.84

0.0046

+3.69

0.00072

-1.71

0.0078

Nsp1

+1.58

0.0050

+3.07

0.014

+1.65

0.017

Pil1

+2.05

0.0013

+9.60

0.0068

+2.65

0.036

Pst2 (a)

+1.50

0.0023

+3.99

0.0074

+1.55

0.0019

Pst2 (b)

+3.83

0.0013

+4.50

0.0074

-1.02

0.14

Rpa1

+3.58

0.00070

+4.16

0.010

-1.33

N/A

Rpa2

+1.47

0.036

+2.50

0.015

-1.12

0.089

Ste4

+1.61

0.023

+2.32

0.000092

-1.00

0.16

Vma2 (a)

+1.92

0.0052

+1.59

0.0063

-1.34

0.00019

Vma2 (b)

+1.48

0.018

+1.64

0.0041

-1.58

0.00018

Vma2 (c)

+1.53

0.0097

+1.65

0.021

+1.10

0.050

Vma4

+1.85

0.010

+1.58

0.0048

-1.08

0.070

Ycp4 (a)

+2.01

0.00070

+5.40

0.00073

+1.76

0.00050

Ycp4 (b)

+1.69

0.037

+5.31

0.00063

+1.18

0.13

Yrb1

+2.05

0.025

+5.07

0.0011

+1.77

0.0040

Hsp31

+1.63

0.0063

-1.64

0.0051

-1.84

0.000062

Rnr4 (a)

+1.91

0.0014

-1.24

0.25

-1.47

0.013

Rnr4 (b)

+3.90

0.000057

-2.08

0.012

-3.11

0.00011

Rnr4 (c)

+3.89

0.000057

-1.17

0.27

-2.23

0.00025

Rnr4 (d)

+2.41

0.0023

-1.06

0.74

+1.30

0.015

Ald6

-1.84

0.00056

-2.21

0.021

-1.81

0.00014

Bgl2

-1.85

0.00068

-1.54

0.17

+7.02

0.000022

Bmh1 (b)

-1.43

0.0020

-1.53

0.0071

-1.07

0.059

Bmh2

-1.90

0.0020

-2.08

0.021

-1.06

0.069

Hsp60

-1.72

0.00017

-1.56

0.091

+1.31

0.0079

Pdc1

-1.69

0.00022

-2.27

0.013

-2.64

0.000099

Rpc40

-1.53

0.0016

+2.31

0.013

+3.98

0.000015

Rpp0

-1.70

0.00056

-2.15

0.028

-1.61

0.00037

Ssb1

-1.62

0.0084

-1.41

0.12

-1.27

0.00027

Ssb2

-1.83

0.0092

+2.01

0.018

+1.45

0.0090

Tma19

-1.93

0.0027

-3.00

0.036

-1.02

0.14

Ura7

-1.85

0.0027

+6.01

0.059

+3.73

0.000022

  1. Multiple protein isoforms are indicated with a, b, c and d in parentheses. DF, differential factor, is fold change in abundance in the chromatin fraction on MMS treatment, where +DF indicates an increase and -DF a decrease. EF is the chromatin enrichment factor relative to the whole cell extract in either treated (MMS+) or control (MMS-) samples. See Additional File 1, Table S2 for MS/MS identification data.
  2. a p-values are calculated using DeCyder 6.0 with FDR correction, from four biological replicates.