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Figure 1 | Proteome Science

Figure 1

From: In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement

Figure 1

Reference gel image of mouse alveolar macrophage proteins identified by 2D-DIGE. Some of the proteins may include multiple spots reflecting different isoforms, fragments, or multimers (see also Additional File 3). 1, 65-kDa macrophage protein; 2, Actin related protein 2/3 complex, subunit 5; 3, Actin-related protein 3; 4, Actr2 protein; 5, Alpha-fetoprotein; 6, Annexin A2; 7, Annexin A4; 8, Anxa5 protein; 9, ArsA arsenite transporter, ATP-binding, homolog 1; 10, Atp5b protein; 11, Calpain, small subunit 1; 12, Capping protein (actin filament) muscle Z-line, alpha 2; 13, Capping protein (actin filament) muscle Z-line, beta isoform a; 14, Cathepsin D precursor; 15, Chaperonin subunit 2 (beta); 16, Chia protein; 17, Chitinase 3-like 3 precursor; 18, Chitinase-related protein MCRP; 19, Chloride intracellular channel 1; 20, Chloride intracellular channel 4; 21, CNDP dipeptidase 2; 22, Coactosin-like 1; 23, EF hand domain containing 2; 24, Eno1 protein (Alpha-enolase); 25, Eukaryotic translation initiation factor 5A; 26, Ezrin; 27, F-actin capping protein alpha-1 subunit; 28, Ferritin heavy chain 1; 29, Ferritin light chain 1; 30, Gamma-actin; 31, Gelsolin precursor; 32, Glucose-6-phosphate dehydrogenase X-linked; 33, Guanine deaminase; 34, Heat shock protein 1, beta; 35, Heat shock protein 5 precursor; 36, Heat shock protein 65; 37, Heat shock protein 8; 38, Heat shock protein 90, beta (Grp94), member 1; 39, Hematopoietic cell specific Lyn substrate 1; 40, Heme-binding protein; 41, Heterogeneous nuclear ribonucleoprotein K; 42, High mobility group 1 protein; 43, Hnrpf protein; 44, Kappa-B motif-binding phosphoprotein; 45, Keratin complex 2, basic, gene 8; 46, Keratin type II; 47, Krt13 protein; 48, Laminin receptor; 49, Major vault protein (MVP); 50, Microtubule-associated protein, RP/EB family, member 1; 51, Myosin light chain, regulatory B-like; 52, Nucleophosmin 1; 53, p50b; 54, Peroxiredoxin 2; 55, Prolyl 4-hydroxylase, beta polypeptide precursor; 56, Proteasome (prosome, macropain) 28 subunit, alpha; 57, Proteasome alpha 1 subunit; 58, Protein disulfide isomerase associated 6; 59, Protein disulfide-isomerase A3 precursor; 60, Protein synthesis initiation factor 4A; 61, Purine nucleoside phosphorylase; 62, Put. beta-actin (aa 27-375); 63, Rab GDP dissociation inhibitor beta; 64, Rho GDP dissociation inhibitor (GDI) alpha; 65, Rho, GDP dissociation inhibitor (GDI) beta; 66, Serine (or cysteine) proteinase inhibitor, clade B, member 1a; 67, Stathmin; 68, Superoxide dismutase 1, soluble; 69, Superoxide dismutase 1, soluble; 70, Tropomyosin 3, gamma; 71, Tubulin, beta 5; 72, Tyrosine 3/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; 73, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; 74, Vacuolar adenosine triphosphatase subunit B; 75, Valosin-containing protein; 76, Vimentin.

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