From: Analysis of protein expression in periodontal pocket tissue: a preliminary study
Systemic Inclusion Criteria | Local Inclusion Criteria |
---|---|
Absence of relevant medical conditions: Medical history of good health (particularly ruling out bone disease, uncontrolled or poorly controlled diabetes, unstable or life-threatening conditions, or requiring antibiotic prophylaxis were excluded). | Defect anatomy: Presence of at least one intrabony defect in patient with periodontal disease. Excessive gingival display or gingival margin asymmetries required a surgical correction in periodontally-healthy patients |
Smoking status: Non-smokers and without a story of alcohol abuse. | Good oral hygiene: full-mouth plaque score (FMPS) ≤20 % |
Compliance: only patients showing high levels of compliance (as assessed during the cause-related phase of therapy) were selected. | Low level of residual infection: full-mouth bleeding score (FMBS) ≤20 %. |
Pregnancy or lactation and underage were excluded. | Endodontic status: Experimental teeth had to be vital or properly treated with root canal therapy. |