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Table 5 Distribution of CysC proteoforms concentrations by albuminuria groups

From: The association of plasma cystatin C proteoforms with diabetic chronic kidney disease

 

N1/N2/N3

Normoalbuminuria

Microalbuminuria

Macroalbuminuria

p-value

Native CysC (mg/L)

78/18/8

1.18 (0.51)

1.56 (0.57)

1.70 (0.68)

0.02a

CysC des-S (mg/L)

78/18/8

0.041 (0.025)

0.053 (0.030)

0.06 (0.019)

0.003b

CysC des-SSP (mg/L)

78/18/8

0.061 (0.047)

0.096(0.071)

0.096 (0.048)

0.01c

  1. Mean (SD). Statistical significance defined with a p < 0.02. Groups compared with ANOVA followed by Tukey’s pairwise comparisons
  2. N1 = number of participants with normoalbuminuria
  3. N2 = number of participants with microalbuminuria
  4. N3 = number of participants with macroalbuminuria
  5. aNative CysC
  6. In macro vs. normoalbuminuria, p = 0.03
  7. In macro vs. microalbuminuria, p = 0.8
  8. In micro vs. normoalbuminuria, p = 0.03
  9. bCysC des-S
  10. In macro vs. normoalbuminuria, p = 0.05
  11. In macro vs. microalbuminuria, p = 0.6
  12. In micro vs. normoalbuminuria, p = 0.2
  13. cCysC des-SSP
  14. In macro vs. normoalbuminuria, p = 0.16
  15. In macro vs. microalbuminuria, p = 0.99
  16. In micro vs. normoalbuminuria, p = 0.02
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