Fig. 2From: Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamics a and b show the solid angle values at the drug binding site of the first trajectory frame of the mutants delE709_T710insD and delL747_T751, respectively. The dark dashed lines indicate the position of 0. c and d demonstrate the number of convex and concave atoms with different solid angle value thresholds at the drug binding site of the two mutantsBack to article page