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Fig. 1 | Proteome Science

Fig. 1

From: Integrated proteome and malonylome analyses reveal the potential meaning of TLN1 and ACTB in end-stage renal disease

Fig. 1

The schematic flow to study the proteome and malonylproteome of peripheral blood mononuclear cells (PBMCs) in End-stage renal disease (ESRD) patients and normal controls (NCs). A Overview of experimental procedures. B Histogram of quantity distribution of differentially expressed proteins (DEPs). Of these 793 DEPs, 302 DEPs were found to be up-regulated and 491 DEPs were down-regulated when compared with the controls. C Histogram of quantity distribution of differentially malonylated proteins (DMPs). 16 malonylation sites were identified in 12 DMPs, among which 8 sites on 7 proteins were hyper-malonylated, while 8 sites on 5 proteins were hypo-malonylated. (Fold change >1.5 or <1/1.5 and P-value <0.05). D In the volcano plots displaying DMPs, TLN1, ACTB and MYH9 are labeled

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Proteome Science

ISSN: 1477-5956