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Table 3 Lung development regulation of 42 DEPs in developing fetal lung

From: Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus

Protein accession

Protein description

Gene name

Ratio

Regulated Type

P25391

Laminin subunit alpha-1

LAMA1

11.154

Up

P48436

Transcription factor SOX-9

SOX9

5.506

Up

Q8IVH2

Forkhead box protein P4

FOXP4

3.686

Up

Q92908

Transcription factor GATA-6

GATA6

3.591

Up

Q63HK5

Teashirt homolog 3

TSHZ3

3.468

Up

P20336

Ras-related protein Rab-3A

RAB3A

3.028

Up

Q9Y618

Nuclear receptor corepressor 2

NCOR2

2.975

Up

P20719

Homeobox protein Hox-A5

HOXA5

2.412

Up

Q02447

Transcription factor Sp3

SP3

2.286

Up

P09429

High mobility group protein B1

HMGB1

2.279

Up

P10600

Transforming growth factor beta-3 proprotein

TGFB3

2.008

Up

Q6NYC1

Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

JMJD6

1.94

Up

O00712

Nuclear factor 1 B-type

NFIB

1.845

Up

P84022

Mothers against decapentaplegic homolog 3

SMAD3

1.838

Up

P51608

Methyl-CpG-binding protein 2

MECP2

1.793

Up

Q9H334

Forkhead box protein P1

FOXP1

1.763

Up

Q99593

T-box transcription factor TBX5

TBX5

1.74

Up

P57082

T-box transcription factor TBX4

TBX4

1.72

Up

Q06330

Recombining binding protein suppressor of hairless

RBPJ

1.669

Up

P04150

Glucocorticoid receptor

NR3C1

1.661

Up

O94880

PHD finger protein 14

PHF14

1.644

Up

Q13948

Protein CASP

CUX1

1.624

Up

P43699

Homeobox protein Nkx-2.1

NKX2-1

1.591

Up

P39880

Homeobox protein cut-like 1

CUX1

1.581

Up

Q9Y547

Intraflagellar transport protein 25 homolog

HSPB11

1.533

Up

P08047

Transcription factor Sp1

SP1

1.528

Up

Q9UPY3

Endoribonuclease Dicer

DICER1

1.527

Up

P09486

SPARC

SPARC

0.661

Down

Q16706

Alpha-mannosidase 2

MAN2A1

0.621

Down

P29466

Caspase-1

CASP1

0.613

Down

P24821

Tenascin

TNC

0.575

Down

Q14118

Dystroglycan

DAG1

0.528

Down

O95994

Anterior gradient protein 2 homolog

AGR2

0.395

Down

P63098

Calcineurin subunit B type 1

PPP3R1

0.362

Down

P38571

Lysosomal acid lipase/cholesteryl ester hydrolase

LIPA

0.316

Down

P09960

Leukotriene A-4 hydrolase

LTA4H

0.277

Down

P54868

Hydroxymethylglutaryl-CoA synthase, mitochondrial

HMGCS2

0.27

Down

P26006

Integrin alpha-3

ITGA3

0.251

Down

O94788

Retinal dehydrogenase 2

ALDH1A2

0.25

Down

Q9UBR2

Cathepsin Z

CTSZ

0.248

Down

Q13510

Acid ceramidase

ASAH1

0.216

Down

P12821

Angiotensin-converting enzyme

ACE

0.199

Down