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Table 2 Qualified performance of models using an independent test set

From: Serum profiling by MALDI-TOF mass spectrometry as a diagnostic tool for domoic acid toxicosis in California sea lions

   3017 m/z ANN 1 ANN 67 ANN 67 ANN 53 CANN-Vote
  Normalization TIC TIC TIC TIC Glu-Fib Glu-Fib
  AuROC 0.7538 0.9412 0.9412 0.9412 0.9428 na
  Threshold a minMC OpT OpT minMC OpT > 50 votes
Test Set sensitivity 0.20 1.00 0.40 0.70 0.30 0.30
  specificity 1.00 0.60 0.90 0.90 1.00 1.00
  PPV 1.00 0.71 0.80 0.88 1.00 1.00
  NPV 0.56 1.00 0.60 0.75 0.59 0.59
Training Set sensitivity 0.35 0.91 0.88 0.91 0.94 1.00
  specificity 0.93 0.95 1.00 0.99 0.96 0.99
  PPV 0.71 0.89 1.00 0.97 0.91 0.97
  NPV 0.76 0.96 0.95 0.96 0.97 1.00
  1. aThresholds calculated a priori based on training set data. minMC, minimum mis-classified threshold; OpT, optimum threshold (OpT).
  2. Performance against training set is given for comparison