TY - JOUR AU - Jiang, X. AU - Zhao, Y. AU - Smith, C. AU - Gasparetto, M. AU - Turhan, A. AU - Eaves, A. AU - Eaves, C. PY - 2007 DA - 2007// TI - Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies JO - Leukemia VL - 21 ID - Jiang2007 ER - TY - JOUR AU - Hochhaus, A. PY - 2006 DA - 2006// TI - Chronic myelogenous leukemia (CML): resistance to tyrosine kinase inhibitors JO - Ann Oncol VL - 17 UR - https://doi.org/10.1093/annonc/mdl273 DO - 10.1093/annonc/mdl273 ID - Hochhaus2006 ER - TY - JOUR AU - Mughal, T. I. AU - Goldman, J. M. PY - 2007 DA - 2007// TI - Emerging strategies for the treatment of mutant Bcr-Abl T315I myeloid leukemia JO - Clin Lymphoma Myeloma VL - 7 UR - https://doi.org/10.3816/CLM.2007.s.006 DO - 10.3816/CLM.2007.s.006 ID - Mughal2007 ER - TY - JOUR AU - Quintás-Cardama, A. AU - Kantarjian, H. M. AU - Cortes, J. E. PY - 2009 DA - 2009// TI - Mechanisms of Primary and Secondary Resistance to Imatinib in Chronic Myeloid Leukemia JO - Cancer Control VL - 16 ID - Quintás-Cardama2009 ER - TY - JOUR AU - Walz, C. AU - Sattler, M. PY - 2006 DA - 2006// TI - Novel targeted therapies to overcome imatinib mesylate resistance in chronic myeloid leukemia JO - Crit Rev Oncol Hematol VL - 57 UR - https://doi.org/10.1016/j.critrevonc.2005.06.007 DO - 10.1016/j.critrevonc.2005.06.007 ID - Walz2006 ER - TY - JOUR AU - Swords, R. AU - Alvarado, Y. AU - Giles, F. PY - 2007 DA - 2007// TI - Novel Abl kinase inhibitors in chronic myeloid leukemia in blastic phase and Philadelphia chromosome-positive acute lymphoblastic leukemia JO - Clin Lymphoma Myeloma VL - 7 UR - https://doi.org/10.3816/CLM.2007.s.011 DO - 10.3816/CLM.2007.s.011 ID - Swords2007 ER - TY - JOUR AU - Azzariti, A. AU - Porcelli, L. AU - Simone, G. M. AU - Quatrale, A. E. AU - Colabufo, N. A. AU - Berardi, F. AU - Perrone, R. AU - Zucchetti, M. AU - D'Incalci, M. AU - Xu, J. M. AU - Paradiso, A. PY - 2009 DA - 2009// TI - Tyrosine kinase inhibitors and multidrug resistance proteins: interactions and biological consequences JO - Cancer Chemother Pharmacol VL - 65 UR - https://doi.org/10.1007/s00280-009-1039-0 DO - 10.1007/s00280-009-1039-0 ID - Azzariti2009 ER - TY - JOUR AU - Mahon, F. AU - Hayette, S. AU - Lagarde, V. AU - Belloc, F. AU - Turcq, B. AU - Nicolini, F. AU - Belanger, C. AU - Manley, P. AU - Leroy, C. AU - Etienne, G. AU - Roche, S. AU - Pasquet, J. PY - 2008 DA - 2008// TI - Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-08-1008 DO - 10.1158/0008-5472.CAN-08-1008 ID - Mahon2008 ER - TY - JOUR AU - Dohse, M. AU - Scharenberg, C. AU - Shukla, S. AU - Robey, R. W. AU - Volkmann, T. AU - Deeken, J. F. AU - Brendel, C. AU - Ambudkar, S. V. AU - Neubauer, A. AU - Bates, S. E. PY - 2010 DA - 2010// TI - Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib JO - Drug Metab Dispos VL - 38 UR - https://doi.org/10.1124/dmd.109.031302 DO - 10.1124/dmd.109.031302 ID - Dohse2010 ER - TY - JOUR AU - Lage, H. PY - 2008 DA - 2008// TI - An overview of cancer multidrug resistance: a still unsolved problem JO - Cell Mol Life Sci VL - 65 UR - https://doi.org/10.1007/s00018-008-8111-5 DO - 10.1007/s00018-008-8111-5 ID - Lage2008 ER - TY - JOUR AU - Stavrovskaya, A. A. AU - Stromskaya, T. P. PY - 2008 DA - 2008// TI - Transport proteins of the ABC family and multidrug resistance of tumor cells JO - Biochemistry (Mosc) VL - 73 UR - https://doi.org/10.1134/S0006297908050118 DO - 10.1134/S0006297908050118 ID - Stavrovskaya2008 ER - TY - JOUR AU - Cristea, I. M. AU - Gaskell, S. J. AU - Whetton, A. D. PY - 2004 DA - 2004// TI - Proteomics techniques and their application to hematology JO - Blood VL - 103 UR - https://doi.org/10.1182/blood-2003-09-3295 DO - 10.1182/blood-2003-09-3295 ID - Cristea2004 ER - TY - JOUR AU - Cho, W. C. PY - 2007 DA - 2007// TI - Contribution of oncoproteomics to cancer biomarker discovery JO - Molecular Cancer VL - 2 ID - Cho2007 ER - TY - JOUR AU - Pizzatti, L. AU - Sá, L. A. AU - De Souza, J. M. AU - Bisch, P. M. AU - Abdelhay, E. PY - 2006 DA - 2006// TI - Altered protein profile in chronic myeloid leukemia chronic phase identified by a comparative proteomic study JO - Biochim Biophys Acta VL - 1764 UR - https://doi.org/10.1016/j.bbapap.2006.02.004 DO - 10.1016/j.bbapap.2006.02.004 ID - Pizzatti2006 ER - TY - JOUR AU - Chuthapisith, S. AU - Layfield, R. AU - Kerr, I. D. AU - Hughes, C. AU - Eremin, O. PY - 2007 DA - 2007// TI - Proteomic profiling of MCF-7 breast cancer cells with chemoresistance to different types of anti-cancer drugs JO - Int J Oncol VL - 30 ID - Chuthapisith2007 ER - TY - JOUR AU - Zeindl-Eberhart, E. AU - Haraida, S. AU - Liebmann, S. AU - Jungblut, P. R. AU - Lamer, S. AU - Mayer, D. AU - Jäger, G. AU - Chung, S. AU - Rabes, H. M. PY - 2004 DA - 2004// TI - Detection and identification of tumor-associated protein variants in human hepatocellular carcinomas JO - Hepatology VL - 39 UR - https://doi.org/10.1002/hep.20060 DO - 10.1002/hep.20060 ID - Zeindl-Eberhart2004 ER - TY - JOUR AU - An, H. J. AU - Kim, D. S. AU - Park, Y. K. AU - Kim, S. K. AU - Choi, Y. P. AU - Kang, S. AU - Ding, B. AU - Cho, N. H. PY - 2006 DA - 2006// TI - Comparative proteomics of ovarian epithelial tumors JO - J Proteome Res VL - 5 UR - https://doi.org/10.1021/pr050461p DO - 10.1021/pr050461p ID - An2006 ER - TY - JOUR AU - Yang, Y. X. AU - Hu, H. D. AU - Zhang, D. Z. AU - Ren, H. PY - 2007 DA - 2007// TI - Identification of Proteins Responsible for the Development of Adriamycin Resistance in Human Gastric Cancer Cells Using Comparative Proteomics Analysis JO - J Biochem Mol Biol VL - 40 UR - https://doi.org/10.5483/BMBRep.2007.40.6.853 DO - 10.5483/BMBRep.2007.40.6.853 ID - Yang2007 ER - TY - JOUR AU - Rumjanek, V. M. AU - Trindade, G. S. AU - Wagner-Souza, K. PY - 2001 DA - 2001// TI - de-Oliveira MC, Marques-Santos LF, Maia RC, Capella MA: Multidrug resistance in tumour cells: characterization of the multidrug resistant cell line K562-Lucena 1 JO - An Acad Bras Cienc VL - 73 UR - https://doi.org/10.1590/S0001-37652001000100007 DO - 10.1590/S0001-37652001000100007 ID - Rumjanek2001 ER - TY - JOUR AU - Assef, Y. AU - Rubio, F. AU - Coló, G. AU - del Mónaco, S. AU - Costas, M. A. AU - Kotsias, B. A. PY - 2009 DA - 2009// TI - Imatinib resistance in multidrug-resistant K562 human leukemic cells JO - Leuk Res VL - 33 UR - https://doi.org/10.1016/j.leukres.2008.09.024 DO - 10.1016/j.leukres.2008.09.024 ID - Assef2009 ER - TY - JOUR AU - Wang, X. AU - Lu, Y. AU - Yang, J. AU - Shi, Y. AU - Lan, M. AU - Liu, Z. AU - Zhai, H. AU - Fan, D. PY - 2008 DA - 2008// TI - Identification of triosephosphate isomerase as an anti-drug resistance agent in human gastric cancer cells using functional proteomic analysis JO - J Cancer Res Clin Oncol VL - 134 UR - https://doi.org/10.1007/s00432-008-0367-5 DO - 10.1007/s00432-008-0367-5 ID - Wang2008 ER - TY - JOUR AU - Roychowdhury, S. AU - Talpaz, M. PY - 2011 DA - 2011// TI - Managing resistance in chronic myeloid leukemia JO - Blood Reviews VL - 25 UR - https://doi.org/10.1016/j.blre.2011.09.001 DO - 10.1016/j.blre.2011.09.001 ID - Roychowdhury2011 ER - TY - JOUR AU - Brózik, A. AU - Hegedüs, C. AU - Erdei, Z. AU - Hegedüs, T. AU - Özvegy-Laczka, C. AU - Szakács, G. AU - Sarkadi, B. PY - 2011 DA - 2011// TI - Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance? JO - Expert Opin Drug Metab Toxicol VL - 7 UR - https://doi.org/10.1517/17425255.2011.562892 DO - 10.1517/17425255.2011.562892 ID - Brózik2011 ER - TY - JOUR AU - Baran, Y. AU - Ural, A. U. AU - Gunduz, U. PY - 2007 DA - 2007// TI - Mechanisms of cellular resistance to imatinib in human chronic myeloid leukemia cells JO - Hematology VL - 12 UR - https://doi.org/10.1080/10245330701384179 DO - 10.1080/10245330701384179 ID - Baran2007 ER - TY - JOUR AU - Baran, Y. AU - Salas, A. AU - Senkal, C. E. AU - Gunduz, U. AU - Bielawski, J. AU - Obeid, L. M. PY - 2007 DA - 2007// TI - Alterations of Ceramide/Sphingosine 1-Phosphate Rheostat Involved in the Regulation of Resistance to Imatinib-induced Apoptosis in K562 Human Chronic Myeloid Leukemia Cells JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M610157200 DO - 10.1074/jbc.M610157200 ID - Baran2007 ER - TY - JOUR AU - Salas, A. AU - Ponnusamy, S. AU - Senkal, C. E. AU - Meyers-Needham, M. AU - Selvam, S. P. AU - Saddoughi, S. A. AU - Apohan, E. AU - Sentelle, R. D. AU - Smith, C. AU - Gault, C. R. AU - Obeid, L. M. AU - El-Shewy, H. M. AU - Oaks, J. AU - Santhanam, R. AU - Marcucci, G. AU - Baran, Y. AU - Mahajan, S. AU - Fernandes, D. AU - Stuart, R. AU - Perrotti, D. AU - Ogretmen, B. PY - 2011 DA - 2011// TI - Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A JO - Blood VL - 117 UR - https://doi.org/10.1182/blood-2010-08-300772 DO - 10.1182/blood-2010-08-300772 ID - Salas2011 ER - TY - JOUR AU - Bewry, N. N. AU - Nair, R. R. AU - Emmons, M. F. AU - Boulware, D. AU - Pinilla-Ibarz, J. AU - Hazlehurst, L. A. PY - 2008 DA - 2008// TI - Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance JO - Mol Cancer Ther VL - 7 UR - https://doi.org/10.1158/1535-7163.MCT-08-0314 DO - 10.1158/1535-7163.MCT-08-0314 ID - Bewry2008 ER - TY - JOUR AU - Kosova, B. AU - Tezcanli, B. AU - Ekiz, H. A. AU - Cakir, Z. AU - Selvi, N. AU - Dalmizrak, A. AU - Kartal, M. AU - Gunduz, U. AU - Baran, Y. PY - 2010 DA - 2010// TI - Suppression of STAT5A increases chemotherapeutic sensitivity in imatinib-resistant and imatinib-sensitive K562 cells JO - Leuk Lymphoma VL - 51 UR - https://doi.org/10.3109/10428194.2010.507830 DO - 10.3109/10428194.2010.507830 ID - Kosova2010 ER - TY - JOUR AU - Nambu, T. AU - Araki, N. AU - Nakagawa, A. AU - Kuniyasu, A. AU - Kawaguchi, T. AU - Hamada, A. AU - Saito, H. PY - 2010 DA - 2010// TI - Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells JO - Cancer Sci VL - 10 UR - https://doi.org/10.1111/j.1349-7006.2009.01365.x DO - 10.1111/j.1349-7006.2009.01365.x ID - Nambu2010 ER - TY - JOUR AU - Mencalha, A. L. AU - Du Rocher, B. AU - Sales, D. AU - Binato, R. AU - Abdelhay, E. PY - 2010 DA - 2010// TI - LLL-3, a STAT3 inhibitor, represses BCR-ABL-positive cell proliferation, activates apoptosis and improves the effects of Imatinib mesylate JO - Cancer Chemother Pharmacol VL - 65 UR - https://doi.org/10.1007/s00280-009-1109-3 DO - 10.1007/s00280-009-1109-3 ID - Mencalha2010 ER - TY - JOUR AU - Graham, S. M. AU - Jorgensen, H. G. AU - Allan, E. AU - Pearson, C. AU - Alcorn, M. J. AU - Richmond, L. AU - Holyoake, T. L. PY - 2002 DA - 2002// TI - Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro JO - Blood VL - 99 UR - https://doi.org/10.1182/blood.V99.1.319 DO - 10.1182/blood.V99.1.319 ID - Graham2002 ER - TY - JOUR AU - Bhatia, R. AU - Holtz, M. AU - Niu, N. AU - Gray, R. AU - Snyder, D. S. AU - Sawyers, C. L. AU - Arber, D. A. AU - Slovak, M. L. AU - Forman, S. J. PY - 2003 DA - 2003// TI - Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients incomplete cytogenetic remission following imatinib mesylate treatment JO - Blood VL - 101 UR - https://doi.org/10.1182/blood-2002-09-2780 DO - 10.1182/blood-2002-09-2780 ID - Bhatia2003 ER - TY - JOUR AU - Angstreich, G. R. AU - Matsui, W. AU - Huff, C. A. AU - Vala, M. S. AU - Barber, J. AU - Hawkins, A. L. AU - Griffin, C. A. AU - Smith, B. D. AU - Jones, R. J. PY - 2005 DA - 2005// TI - Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors JO - Br J Haematol VL - 130 UR - https://doi.org/10.1111/j.1365-2141.2005.05606.x DO - 10.1111/j.1365-2141.2005.05606.x ID - Angstreich2005 ER - TY - JOUR AU - Copland, M. AU - Hamilton, A. AU - Elrick, L. J. AU - Baird, J. W. AU - Allan, E. K. AU - Jordanides, N. AU - Barow, M. AU - Mountford, J. C. AU - Holyoake, T. L. PY - 2006 DA - 2006// TI - Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction JO - Blood VL - 107 UR - https://doi.org/10.1182/blood-2005-07-2947 DO - 10.1182/blood-2005-07-2947 ID - Copland2006 ER - TY - JOUR AU - Nicholson, E. AU - Holyoake, T. PY - 2009 DA - 2009// TI - The chronic myeloid leukemia stem cell JO - Clin Lymphoma Myeloma VL - 9 UR - https://doi.org/10.3816/CLM.2009.s.037 DO - 10.3816/CLM.2009.s.037 ID - Nicholson2009 ER - TY - CHAP AU - Hamilton, A. AU - Helgason, G. V. AU - Schemionek, M. AU - Zhang, B. AU - Myssina, S. AU - Allan, E. K. AU - Nicolini, F. E. AU - Müller-Tidow, C. AU - Bhatia, R. AU - Brunton, V. G. AU - Koschmieder, S. AU - Holyoake, T. L. PY - 2011 DA - 2011// TI - Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival BT - Blood ID - Hamilton2011 ER - TY - JOUR AU - Mukai, M. AU - Che, X. F. AU - Furukawa, T. AU - Sumizawa, T. AU - Aoki, S. AU - Ren, X. Q. AU - Haraguchi, M. AU - Sugimoto, Y. AU - Kobayashi, M. AU - Takamatsu, H. AU - Akiyama, S. PY - 2003 DA - 2003// TI - Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells JO - Cancer Sci VL - 94 UR - https://doi.org/10.1111/j.1349-7006.2003.tb01482.x DO - 10.1111/j.1349-7006.2003.tb01482.x ID - Mukai2003 ER - TY - JOUR AU - Illmer, T. AU - Schaich, M. AU - Platzbecker, U. AU - Freiberg-Richter, J. AU - Oelschlägel, U. AU - von Bonin, M. AU - Pursche, S. AU - Bergemann, T. AU - Ehninger, G. AU - Schleyer, E. PY - 2004 DA - 2004// TI - P-glycoprotein-mediated drug efflux is a resistance mechanism of chronic myelogenous leukemia cells to treatment with imatinib mesylate JO - Leukemia VL - 18 UR - https://doi.org/10.1038/sj.leu.2403257 DO - 10.1038/sj.leu.2403257 ID - Illmer2004 ER - TY - JOUR AU - Yamada, O. AU - Ozaki, K. AU - Furukawa, T. AU - Machida, M. AU - Wang, Y. AU - Motoji, T. AU - Mitsuishi, T. AU - Akiyama, M. AU - Yamada, H. PY - 2011 DA - 2011// TI - Activation of STAT5 confers imatinib resistance on leukemic cells through the transcription of TER and MDR JO - Cell Signal VL - 23 UR - https://doi.org/10.1016/j.cellsig.2011.02.005 DO - 10.1016/j.cellsig.2011.02.005 ID - Yamada2011 ER - TY - JOUR AU - Haouala, A. AU - Widmer, N. AU - Duchosal, M. A. AU - Montemurro, M. AU - Buclin, T. AU - Decosterd, L. A. PY - 2011 DA - 2011// TI - Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib JO - Blood VL - 117 UR - https://doi.org/10.1182/blood-2010-07-294330 DO - 10.1182/blood-2010-07-294330 ID - Haouala2011 ER - TY - JOUR AU - Vasconcelos, F. AU - Silva, K. AU - Souza, P. AU - Silva, L. AU - Moellmann-Coelho, A. AU - Klumb, C. AU - Maia, R. PY - 2011 DA - 2011// TI - Variation of MDR Proteins Expression and Activity Levels According to Clinical Status and Evolution of CML Patients JO - Cytometry B Clin Cytom VL - 80 UR - https://doi.org/10.1002/cyto.b.20580 DO - 10.1002/cyto.b.20580 ID - Vasconcelos2011 ER - TY - JOUR AU - Wang, X. J. AU - Sun, Z. AU - Villeneuve, N. F. AU - Zhang, S. AU - Zhao, F. AU - Li, Y. AU - Chen, W. AU - Yi, X. AU - Zheng, W. AU - Wondrak, G. T. AU - Wong, P. K. AU - Zhang, D. D. PY - 2008 DA - 2008// TI - Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2 JO - Carcinogenesis VL - 29 UR - https://doi.org/10.1093/carcin/bgn095 DO - 10.1093/carcin/bgn095 ID - Wang2008 ER - TY - JOUR AU - Ma, Q. PY - 2008 DA - 2008// TI - Xenobiotic-activated receptors: from transcription to drug metabolism to disease JO - Chem Res Toxicol VL - 21 UR - https://doi.org/10.1021/tx800156s DO - 10.1021/tx800156s ID - Ma2008 ER - TY - JOUR AU - Hayashibara, T. AU - Yamada, Y. AU - Mori, N. AU - Harasawa, H. AU - Sugahara, K. AU - Miyanishi, T. AU - Kamihira, S. AU - Tomonaga, M. PY - 2003 DA - 2003// TI - Possible involvement of aryl hydrocarbon receptor (AhR) in adult T-cell leukemia (ATL) leukemogenesis: constitutive activation of AhR in ATL JO - Biochem Biophys Res Commun VL - 300 UR - https://doi.org/10.1016/S0006-291X(02)02793-6 DO - 10.1016/S0006-291X(02)02793-6 ID - Hayashibara2003 ER - TY - JOUR AU - Kizu, R. AU - Okamura, K. AU - Toriba, A. AU - Kakishima, H. AU - Mizokami, A. AU - Burnstein, K. L. AU - Hayakawa, K. PY - 2003 DA - 2003// TI - A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells JO - Arch Toxicol VL - 77 ID - Kizu2003 ER - TY - JOUR AU - Giudice, A. PY - 2010 DA - 2010// TI - C. Arra C, M.C. Turco MC: Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents JO - Methods Mol Biol VL - 647 UR - https://doi.org/10.1007/978-1-60761-738-9_3 DO - 10.1007/978-1-60761-738-9_3 ID - Giudice2010 ER - TY - JOUR AU - Tarumoto, T. AU - Nagai, T. AU - Ohmine, K. AU - Miyoshi, T. AU - Nakamura, M. AU - Kondo, T. AU - Mitsugi, K. AU - Nakano, S. AU - Muroi, K. AU - Komatsu, N. AU - Ozawa, K. PY - 2004 DA - 2004// TI - Ascorbic acid restores sensitivity to imatinib via suppression of Nrf2-dependent gene expression in the imatinib-resistant cell line JO - Exp Hematol VL - 32 UR - https://doi.org/10.1016/j.exphem.2004.01.007 DO - 10.1016/j.exphem.2004.01.007 ID - Tarumoto2004 ER - TY - JOUR AU - Colavita, I. AU - Esposito, N. AU - Martinelli, R. AU - Catanzano, F. AU - Melo, J. V. AU - Pane, F. AU - Ruoppolo, M. AU - Salvatore, F. PY - 2010 DA - 2010// TI - Gaining insights into the Bcr-Abl activity-independent mechanisms of resistance to imatinib mesylate in KCL22 cells: A comparative proteomic approach JO - Biochim Biophys Acta VL - 1804 UR - https://doi.org/10.1016/j.bbapap.2010.04.009 DO - 10.1016/j.bbapap.2010.04.009 ID - Colavita2010 ER - TY - JOUR AU - Nagai, T. AU - Kikuchi, S. AU - Ohmine, K. AU - Miyoshi, T. AU - Nakamura, M. AU - Kondo, T. AU - Furuyama, K. AU - Komatsu, N. AU - Ozawa, K. PY - 2008 DA - 2008// TI - Hemin reduces cellular sensitivity to imatinib and anthracyclins via Nrf2 JO - J Cell Biochem VL - 104 UR - https://doi.org/10.1002/jcb.21659 DO - 10.1002/jcb.21659 ID - Nagai2008 ER - TY - JOUR AU - Bonovolias, I. D. AU - Tsiftsoglou, A. S. PY - 2009 DA - 2009// TI - Hemin counteracts the repression of Bcl-2 and NrF2 genes and the cell killing induced by imatinib in human Bcr-Abl(+) CML cells JO - Oncol Res VL - 17 UR - https://doi.org/10.3727/096504009789745557 DO - 10.3727/096504009789745557 ID - Bonovolias2009 ER - TY - JOUR AU - Hou, J. AU - Wang, F. AU - McKeehan, W. L. PY - 1994 DA - 1994// TI - Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2) JO - In Vitro Cell Dev Biol Anim VL - 30 UR - https://doi.org/10.1007/BF02631402 DO - 10.1007/BF02631402 ID - Hou1994 ER - TY - JOUR AU - Liu, L. AU - McKeehan, W. L. PY - 2002 DA - 2002// TI - Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity JO - Genomics VL - 79 UR - https://doi.org/10.1006/geno.2001.6679 DO - 10.1006/geno.2001.6679 ID - Liu2002 ER - TY - JOUR AU - Liu, L. AU - Amy, V. AU - Liu, G. AU - McKeehan, W. L. PY - 2002 DA - 2002// TI - Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells JO - In Vitro Cell Dev Biol Anim VL - 38 UR - https://doi.org/2.0.CO;2 DO - 2.0.CO;2 ID - Liu2002 ER - TY - JOUR AU - Labialle, S. AU - Dayan, G. AU - Gayet, L. AU - Rigal, D. AU - Gambrelle, J. AU - Baggetto, L. G. PY - 2004 DA - 2004// TI - New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving the LRP130 protein JO - Nucleic Acids Res VL - 32 UR - https://doi.org/10.1093/nar/gkh722 DO - 10.1093/nar/gkh722 ID - Labialle2004 ER - TY - JOUR AU - Michaud, M. AU - Barakat, S. AU - Magnard, S. AU - Rigal, D. AU - Baggetto, L. G. PY - 2011 DA - 2011// TI - Leucine-rich protein 130contributes to apoptosis resistance in human hepatocarcinoma cells JO - Intern Journal of Oncol VL - 38 ID - Michaud2011 ER - TY - JOUR AU - Takisawa, H. AU - Mimura, S. AU - Kubota, Y. PY - 2000 DA - 2000// TI - Eukaryotic DNA replication: from pre-replication complex to initiation complex JO - Curr Opin Cell Biol VL - 12 UR - https://doi.org/10.1016/S0955-0674(00)00153-8 DO - 10.1016/S0955-0674(00)00153-8 ID - Takisawa2000 ER - TY - JOUR AU - Shohet, J. M. AU - Hicks, M. J. AU - Plon, S. E. AU - Burlingame, S. M. AU - Stuart, S. AU - Chen, S. Y. AU - Brenner, M. K. AU - Nuchtern, J. G. PY - 2002 DA - 2002// TI - Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma JO - Cancer Res VL - 62 ID - Shohet2002 ER - TY - JOUR AU - Blanc, E. AU - Goldschneider, D. AU - Ferrandis, E. AU - Barrois, M. AU - Le Roux, G. AU - Leonce, S. AU - Douc-Rasy, S. AU - Bénard, J. AU - Raguénez, G. PY - 2003 DA - 2003// TI - MYCN enhances P-gp/MDR1 gene expression in the human metastatic neuroblastoma IGR-N-91 model JO - Am J Pathol VL - 163 UR - https://doi.org/10.1016/S0002-9440(10)63656-5 DO - 10.1016/S0002-9440(10)63656-5 ID - Blanc2003 ER - TY - JOUR AU - Pajic, M. AU - Norris, M. D. AU - Cohn, S. L. AU - Haber, M. PY - 2005 DA - 2005// TI - The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome JO - Cancer Lett VL - 228 UR - https://doi.org/10.1016/j.canlet.2005.01.060 DO - 10.1016/j.canlet.2005.01.060 ID - Pajic2005 ER - TY - JOUR AU - Tsao, C. C. AU - Geisen, C. AU - Abraham, R. T. PY - 2004 DA - 2004// TI - Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling JO - EMBO J VL - 23 UR - https://doi.org/10.1038/sj.emboj.7600463 DO - 10.1038/sj.emboj.7600463 ID - Tsao2004 ER - TY - JOUR AU - Cortez, D. AU - Glick, G. PY - 2004 DA - 2004// TI - Elledge SJ: Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases JO - Proc Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0403410101 DO - 10.1073/pnas.0403410101 ID - Cortez2004 ER - TY - JOUR AU - Chou, D. M. AU - Elledge, S. J. PY - 2006 DA - 2006// TI - Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function JO - Proc Natl Acad Sci USA VL - 103 UR - https://doi.org/10.1073/pnas.0609251103 DO - 10.1073/pnas.0609251103 ID - Chou2006 ER - TY - JOUR AU - Mahon, F. X. AU - Deininger, M. AU - Schultheis, B. AU - Chabrol, J. AU - Reiffers, J. AU - Goldman, J. M. AU - Melo, J. V. PY - 2000 DA - 2000// TI - Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the signal transduction inhibitor STI571: diverse mechanisms of resistance JO - Blood VL - 96 ID - Mahon2000 ER - TY - JOUR AU - Reis, F. R. AU - Vasconcelos, F. C. AU - Pereira, D. L. AU - Moellman-Coelho, A. AU - Silva, K. L. AU - Maia, R. C. PY - 2011 DA - 2011// TI - Survivin and P-glycoprotein are associated and highly expressed in late phase chronic myeloid leukemia JO - Oncol Rep VL - 26 ID - Reis2011 ER - TY - JOUR AU - Ferrao, P. T. AU - Frost, M. J. AU - Siah, S. P. AU - Ashman, L. K. PY - 2003 DA - 2003// TI - Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro JO - Blood VL - 102 UR - https://doi.org/10.1182/blood-2003-01-0083 DO - 10.1182/blood-2003-01-0083 ID - Ferrao2003 ER - TY - JOUR AU - Dai, H. AU - Marbach, P. AU - Lemaire, M. AU - Hayes, M. AU - Elmquist, W. F. PY - 2003 DA - 2003// TI - Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux JO - J Pharmacol Exp Ther VL - 304 UR - https://doi.org/10.1124/jpet.102.045260 DO - 10.1124/jpet.102.045260 ID - Dai2003 ER - TY - JOUR AU - Mahon, F. X. AU - Belloc, F. AU - Lagarde, V. AU - Chollet, C. AU - Moreau-Gaudry, F. AU - Reiffers, J. AU - Goldman, J. M. AU - Melo, J. V. PY - 2003 DA - 2003// TI - MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models JO - Blood VL - 101 UR - https://doi.org/10.1182/blood.V101.6.2368 DO - 10.1182/blood.V101.6.2368 ID - Mahon2003 ER - TY - JOUR AU - Thomas, J. AU - Wang, L. AU - Clark, R. E. AU - Pirmohamed, M. PY - 2004 DA - 2004// TI - Active transport of imatinib into and out of cells: implications for drug resistance JO - Blood VL - 104 UR - https://doi.org/10.1182/blood-2003-12-4276 DO - 10.1182/blood-2003-12-4276 ID - Thomas2004 ER - TY - JOUR AU - Galimberti, S. AU - Cervetti, G. AU - Guerrini, F. AU - Testi, R. AU - Pacini, S. AU - Fazzi, R. AU - Simi, P. AU - Petrini, M. PY - 2005 DA - 2005// TI - Quantitative molecular monitoring of BCR-ABL and MDR1 transcripts in patients with chronic myeloid leukemia during Imatinib treatment JO - Cancer Genet Cytogenet VL - 162 UR - https://doi.org/10.1016/j.cancergencyto.2005.01.015 DO - 10.1016/j.cancergencyto.2005.01.015 ID - Galimberti2005 ER - TY - JOUR AU - Ni, L. N. AU - Li, J. Y. AU - Miao, K. R. AU - Qiao, C. AU - Zhang, S. J. AU - Qiu, H. R. AU - Qian, S. X. PY - 2011 DA - 2011// TI - Multidrug resistance gene (MDR1) polymorphisms correlate with imatinib response in chronic myeloid leukemia JO - Med Oncol VL - 28 UR - https://doi.org/10.1007/s12032-010-9456-9 DO - 10.1007/s12032-010-9456-9 ID - Ni2011 ER - TY - JOUR AU - Yamakawa, Y. AU - Hamada, A. AU - Nakashima, R. AU - Yuki, M. AU - Hirayama, C. AU - Kawaguchi, T. AU - Saito, H. PY - 2011 DA - 2011// TI - Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia JO - Ther Drug Monit VL - 33 ID - Yamakawa2011 ER - TY - JOUR AU - Deenik, W. AU - van der Holt, B. AU - Janssen, J. J. W. M. AU - Chu, I. W. T. AU - Valk, P. J. M. AU - Ossenkoppele, G. J. AU - van der Heiden, I. P. PY - 2010 DA - 2010// TI - P. Sonneveid P, van Schaik RHN, Cornelissen JJ: Polymorphisms in the multidrug resistance gene MDR1 (ABCB1) predict for molecular resistance in patients with newly diagnosed chronic myeloid leukemia receiving high-dose imatinib JO - Blood VL - 116 UR - https://doi.org/10.1182/blood-2010-07-296954 DO - 10.1182/blood-2010-07-296954 ID - Deenik2010 ER - TY - JOUR AU - Zhou, S. AU - Schuetz, J. D. AU - Bunting, K. D. AU - Colapietro, A. M. AU - Sampath, J. AU - Morris, J. J. AU - Lagutina, I. AU - Grosveld, G. C. AU - Osawa, M. AU - Nakauchi, H. AU - Sorrentino, B. P. PY - 2001 DA - 2001// TI - The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype JO - Nat Med VL - 7 UR - https://doi.org/10.1038/nm0901-1028 DO - 10.1038/nm0901-1028 ID - Zhou2001 ER - TY - JOUR AU - Jordanides, N. E. AU - Jorgensen, H. G. AU - Holyoake, T. L. AU - Mountford, J. C. PY - 2006 DA - 2006// TI - Functional ABCG2 is overexpressed on primary CML CD34+ cells and is inhibited by imatinib mesylate JO - Blood VL - 108 UR - https://doi.org/10.1182/blood-2006-02-003145 DO - 10.1182/blood-2006-02-003145 ID - Jordanides2006 ER - TY - JOUR AU - Jiang, X. AU - Zhao, Y. AU - Smith, C. AU - Gasparetto, M. AU - Turhan, A. AU - Eaves, A. AU - Eaves, C. PY - 2007 DA - 2007// TI - Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies JO - Leukemia VL - 21 ID - Jiang2007 ER - TY - JOUR AU - Hatziieremia, S. AU - Jordanides, N. E. AU - Holyoake, T. L. AU - Mountford, J. C. AU - Jørgensen, H. G. PY - 2009 DA - 2009// TI - Inhibition of MDR1 does not sensitize primitive chronic myeloid leukemia CD34+ cells to imatinib JO - Exp Hematol VL - 37 UR - https://doi.org/10.1016/j.exphem.2009.02.006 DO - 10.1016/j.exphem.2009.02.006 ID - Hatziieremia2009 ER - TY - JOUR AU - Zong, Y. AU - Zhou, S. AU - Sorrentino, B. P. PY - 2005 DA - 2005// TI - Loss of P-glycoprotein expression in hematopoietic stem cells does not improve responses to imatinib in a murine model of chronic myelogenous leukemia JO - Leukemia VL - 19 UR - https://doi.org/10.1038/sj.leu.2403853 DO - 10.1038/sj.leu.2403853 ID - Zong2005 ER - TY - JOUR AU - Leth-Larsen, R. AU - Lund, R. R. AU - Ditzel, H. J. PY - 2010 DA - 2010// TI - Plasma membrane proteomics and its application in clinical cancer biomarker discovery JO - Mol Cell Proteomics VL - 9 UR - https://doi.org/10.1074/mcp.R900006-MCP200 DO - 10.1074/mcp.R900006-MCP200 ID - Leth-Larsen2010 ER - TY - JOUR AU - Rocha, G. G. AU - Simões, M. AU - Oliveira, R. R. AU - Kaplan, M. A. C. AU - Gattass, C. R. PY - 2012 DA - 2012// TI - 3β-acetyl tormentic acid induces apoptosis of resistant leukemia cells independently of P-gp/ABCB1 activity or expression JO - Invest New Drugs VL - 30 UR - https://doi.org/10.1007/s10637-010-9524-1 DO - 10.1007/s10637-010-9524-1 ID - Rocha2012 ER - TY - JOUR AU - Nicoletti, I. AU - Migliorati, G. AU - Pagliaccil, M. C. AU - Grignani, F. AU - Riccardi, C. PY - 1991 DA - 1991// TI - A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry JO - J Immunol Methods VL - 139 UR - https://doi.org/10.1016/0022-1759(91)90198-O DO - 10.1016/0022-1759(91)90198-O ID - Nicoletti1991 ER - TY - JOUR AU - Neyfakh, A. A. PY - 1988 DA - 1988// TI - Use of fluorescent dyes as molecular probes for the study of multidrug resistance JO - Exp Cell Res VL - 174 UR - https://doi.org/10.1016/0014-4827(88)90152-8 DO - 10.1016/0014-4827(88)90152-8 ID - Neyfakh1988 ER - TY - JOUR AU - Bradford, M. M. PY - 1976 DA - 1976// TI - A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding JO - Anal Biochem VL - 72 UR - https://doi.org/10.1016/0003-2697(76)90527-3 DO - 10.1016/0003-2697(76)90527-3 ID - Bradford1976 ER - TY - JOUR AU - Candiano, G. AU - Bruschi, M. AU - Musante, L. AU - Santucci, L. AU - Ghiggeri, G. M. AU - Carnemolla, B. AU - Orecchia, P. AU - Zardi, L. AU - Righetti, P. G. PY - 2004 DA - 2004// TI - Blue silver: a very sensitive colloidal Coomassie G-250 staining for proteome analysis JO - Electrophoresis VL - 25 UR - https://doi.org/10.1002/elps.200305844 DO - 10.1002/elps.200305844 ID - Candiano2004 ER - TY - JOUR AU - Livak, K. J. AU - Schmittgen, T. D. PY - 2001 DA - 2001// TI - Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)) Method JO - Methods VL - 25 UR - https://doi.org/10.1006/meth.2001.1262 DO - 10.1006/meth.2001.1262 ID - Livak2001 ER -