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Figure 9 | Proteome Science

Figure 9

From: A comparative proteomic study identified LRPPRC and MCM7 as putative actors in imatinib mesylate cross-resistance in Lucena cell line

Figure 9

Real-time quantitative PCR analysis of target gene expression in healthy donors and CML patients. Total RNA was isolated from bone marrow donors and CML patients and examined by RT-qPCR to determine changes in mRNA levels. Raw expression values were normalized to β-actin expression. Analyses of ABCB1, ABCG2, OCT1, RBM17, LRPPRC and MCM7 expression changes were performed in 6 donors, 5 IM-responsive patients and 9 IM-resistant patients. Values represent the means of three independent determinations ± s.d. (*p < 0.05). Resp. P = responsive patients; Resist. P. = resistant patients.

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Proteome Science

ISSN: 1477-5956