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Figure 1 | Proteome Science

Figure 1

From: Vigilin interacts with signal peptide peptidase

Figure 1

SPP exists in higher molecular weight complexes. Top panel, HEK293 lysate solubilized in 0.5% DDM and resolved on 16% Bis-Tris Blue Native-PAGE gels, revealing SPP-containing complexes at around 450 kDa, 200 kDa and 100 kDa. Lower panel, lysates resolved on the BN-PAGE were then resolved on the second dimension/SDS-PAGE. SDS-stable SPP dimer can be found in all three high molecular weight bands suggesting that the 100 kDa band observed in the first dimension is a SDS-stable SPP dimer.

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Proteome Science

ISSN: 1477-5956