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Table 3 AUC obtained by leave-one-out internal validation (LOO) with the optimal median and mean number of peaks per iteration

From: Proteomic biomarkers predicting lymph node involvement in serum of cervical cancer patients. Limitations of SELDI-TOF MS

 

LOO AUC (SE)

Sensitivity

Specificity

Median number of peaks per LOO iteration

Mean number of peaks per LOO iteration (SD)

Lymph node status

 Negative vs Positive

0.95 (0.03)

73.9

91.7

1

1 (0)

Histological subtype

 Squamous ca. vs adenoca.

0.88 (0.05)

88.2

59.0

1

1 (0)

 Squamous ca. vs adsq ca.

0.85 (0.06)

84.6

100

4

3.8 (0.9)

 Adenoca. vs adsq ca.

0.94 (0.06)

94.1

100

1

0.9 (0.3)

LVSI

 Negative vs Positive

0.81 (0.06)

78.1

73.1

1

1 (0)

Recurrence

 Negative vs Positive

0.92 (0.04)

79.2

90.0

3

3 (0)

  1. Abbreviations: SE = standard error; SD = standard deviation; ca. = carcinoma; Adsq ca. = Adenosquamous carcinoma; LVSI = lymph vascular space involvement.