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Table 3 AUC obtained by leave-one-out internal validation (LOO) with the optimal median and mean number of peaks per iteration

From: Proteomic biomarkers predicting lymph node involvement in serum of cervical cancer patients. Limitations of SELDI-TOF MS

  LOO AUC (SE) Sensitivity Specificity Median number of peaks per LOO iteration Mean number of peaks per LOO iteration (SD)
Lymph node status
 Negative vs Positive 0.95 (0.03) 73.9 91.7 1 1 (0)
Histological subtype
 Squamous ca. vs adenoca. 0.88 (0.05) 88.2 59.0 1 1 (0)
 Squamous ca. vs adsq ca. 0.85 (0.06) 84.6 100 4 3.8 (0.9)
 Adenoca. vs adsq ca. 0.94 (0.06) 94.1 100 1 0.9 (0.3)
LVSI
 Negative vs Positive 0.81 (0.06) 78.1 73.1 1 1 (0)
Recurrence
 Negative vs Positive 0.92 (0.04) 79.2 90.0 3 3 (0)
  1. Abbreviations: SE = standard error; SD = standard deviation; ca. = carcinoma; Adsq ca. = Adenosquamous carcinoma; LVSI = lymph vascular space involvement.