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Table 1 Comparison of detected peaks in serum and tissue

From: A critical assessment of SELDI-TOF-MS for biomarker discovery in serum and tissue of patients with an ovarian mass

 

Serum

Tissue

 

m/z

adjusted p-value

FC

m/z

adjusted p-value

FC

CM10

10844

<0.0001

2.35

11753

<0.0001

4.11

 

2773

<0.0001

0.57

4309

<0.0001

0.09

 

3784

<0.0001

0.46

11855

<0.0001

3.48

 

5963

<0.0001

1.76

12294

<0.0001

4.84

 

2719

<0.0001

0.61

6652

<0.0001

2.39

 

6048

<0.0001

1.60

6987

<0.0001

2.16

 

6081

<0.0001

1.61

3139

<0.0001

0.21

 

2796

<0.0001

0.58

9983

<0.0001

2.00

 

5820

<0.0001

1.77

24815

<0.0001

1.99

 

4296

<0.0001

0.51

5768

<0.0001

0.31

Q10

6685

<0.0001

0.64

3783

<0.0001

12.23

 

3694

<0.0001

0.62

2774

<0.0001

0.11

 

4288

<0.0001

0.70

4219

<0.0001

0.31

 

4685

<0.0001

1.31

3958

<0.0001

2.85

 

4796

0.0001

1.64

2923

<0.0001

2.85

 

2909

0.0002

0.68

5460

<0.0001

0.19

 

2858

0.0002

0.70

2944

0.0001

1.99

 

1910

0.0005

0.69

4298

0.0007

0.36

 

7994

0.0005

1.54

8198

0.0007

1.99

 

4631

0.0012

1.24

5198

0.0009

1.80

  1. List of ten m/z values most differentially expressed when comparing cancer with benign tumors in the serum and tissue experiments. Peaks listed are after pre-processing for CM10 and Q10 arrays. For each of the m/z values the adjusted p-value and fold change (FC: cancer versus benign) is given.
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