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Figure 3 | Proteome Science

Figure 3

From: Protein and phosphoprotein levels in glioma and adenocarcinoma cell lines grown in normoxia and hypoxia in monolayer and three-dimensional cultures

Figure 3

Protein changes from ANOVA of 3D-2D (monolayer to 3D) medium by cell line whether normoxic or hypoxic conditions for proteins with p-value < 0.05. Proteins are ordered from based on the FC (fold change) and scored -1, 0, or +1, depending on quartile distribution of raw antibody difference values (-1, blue, lowest quartile; +1, red, highest quartile; 0, green, others). Also shown is the score when > 50% of the total for glioma (GL; 6/10) and adenocarcinoma (AC; 7/12) values move in the same direction. The data is divided into six groupings based on > 50% score (+1, -1, and 0) for gliomas (GL) and adenocarcinomas (AC) together and separately as well as neutral and ill-defined scores. The Sum Score at the bottom of the figure is the summed values for columns in figures 2 and 3.

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