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Figure 5 | Proteome Science

Figure 5

From: Human giant congenital melanocytic nevus exhibits potential proteomic alterations leading to melanotumorigenesis

Figure 5

Protein-protein interaction map of GCMN and melanoma. A. GCMN and melanoma show five common upregulated proteins, namely PHB, HSPB1, ANXA2, CTSD, and EEF1A1. There are 217 cross-interactions between the GCMN and melanoma proteome. B. A total of 23 proteins (6 proteins from the GCNM proteome and 17 proteins from the melanoma proteome) interact with the differentially expressed 14-3-3 protein family in GCMN. Two interacting proteins, PHB and EEF1A1, were co-detected in both groups.

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Proteome Science

ISSN: 1477-5956