Table 3 Functional classification of the proteins selected after ICPL™
From: Isotope Coded Protein Labeling analysis of plasma specimens from acute severe dengue fever patients
Over represented in DF pool | Over represented in SD pool | Functional category | Subcellular location | Comments |
|---|---|---|---|---|
Peroxiredoxin 2 | - | Oxidative stress regulatory protein | Cytosol | Interacts with G3BP |
- | Galectin-3 Binding Protein (G3BP) | cell-cell and cell-matrix interactions; immune response (natural killer and cytotoxicity) | Secreted | Interacts with Peroxiredoxin 2 |
- | Vitamin D Binding-Protein | Multifunctional; Vitamin D transportation (albumin protein familly) | Secreted | - |
- | Afamin | Multifunctional; Vitamin E transportation (albumin protein family) | Secreted | - |
- | Fibronectin | Cell migration, adhesion and matrix organization | Secreted | Interacts with LRG1 |
- | Leucine-Rich Glycoprotein 1(LRG1) | protein-protein interaction, signal transduction, and cell adhesion and development | Secreted | Interacts with Fibronectin |
- | C-Reactive Protein | Response to inflammation | Secreted | - |
- | Ferritin LC | Iron storage and release | Cytosol | - |