A comparison of E15.5 fetus and newborn rat serum proteomes

Table 1 Results from our study compared to results obtained prior to the modern era of proteomics

*Protein name*	*Our result*	*Published result*	*Species and reference*
Serum albumin	↑	↑	Rat [11], Pig [24], Chicken [13], Human [22], Porcine [27]
Isoform 1 of Serotransferrin	↑	↑	Rat [11] Human [21, 22], Pig [25]
		∧	Porcine [27]
		↓	Pig [24]
Complement C3	↑	↑	Human [21]
Complement C3		↓	Pig [24]
Alpha-2-macroglobulin	↑	↑	Human [21]
Plasminogen	↑	↑	Human [21, 22]
Plasminogen		↓	Pig [24]
Isoform 1 of Haptoglobin	↑	#	Human [21]
Alpha-2-HS-glycoprotein	↑	↑	Human [22]
Transthyretin	↑	↑	Human [22]
Fetuin-B	↑	↑	Porcine [27],
Fetuin-B		↑ or ↓	Pig [24]
Retinol-binding protein 4	↑	↑	Human [22]
Ceruloplasmin	↑	#	Human [21]
Fibrinogen-like 2	↑	#	Human [21]
Alpha-1-acid glycoprotein	↑	↑	Pig [24], Porcine [27]
Apolipoprotein H	↑	↑	Pig [24]
Angiotensinogen	↑	↓	Pig [24]
Hemopexin	↓	↑	Human [21]
Apolipoprotein A-I	↓	↑	Human [22]
Apolipoprotein E	↓	↑	Human [22]
Apolipoprotein A-IV	↓	↑	Human [22]
Gamma-A of Fibrinogen gamma chain	↓	#	Human [21]
Isoform 1 of Alpha-fetoprotein	↓	↓	Human [22], Pig [24, 25],
		∧	Porcine [27]

Note: Proteins changed from E15.5 fetuses to newborn rats and proteins changed with development in literature were noted using an increasing arrow (↑) / decreasing arrow (↓). Proteins without information on expression changes are indicated with “#”. Protein expression that increased during the early stage of development and decreases in the late stage of development is indicated with “∧”.

ISSN: 1477-5956