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Table 1 Partial lists of differentially regulated proteins in neonatal thymus group identified by MS *

From: Proteomics identifies differentially expressed proteins in neonatal murine thymus compared with adults

Accession No.

Protein name

Gene name

pI/MW

Mass matched

Protein covered (%)

Mascot score

t - test value

Fold change

TENA_MOUSE

Tenascin

Tnc

4.77/237

11/22

8

70

0.00019

2.03↑

ACTN4_MOUSE

Actinin-4

Actn4

5.25/105

16/42

21

93

0.000054

1.74↑

TRAP1_MOUSE

Heat shock protein 75 kDa

Trap1

6.25/81

22/35

35

212

0.0000037

1.54↑

GRP75_MOUSE

Stress-70 protein

Hspa9

5.91/74

19/29

29

166

0.0000022

1.65↑

CH60_MOUSE

60 kDa heat shock protein

Hspd1

5.91/61

13/25

32

129

0.00012

1.90↑

ATPB_MOUSE

ATP synthase subunit beta

Atp5b

5.19/56

21/24

58

253

0.0000023

2.45↑

SEPT7_MOUSE

Septin-7

Sept7

8.73/51

4/16

12

103

0.000071

2.72↑

ACTB_MOUSE

Beta-actin

Actb

5.29/42

15/45

42

109

0.000075

2.20↑

STML2_MOUSE

Stomatin-like protein 2

Stoml2

8.95/38

14/24

45

165

0.00000052

2.70↑

PSME1_MOUSE

Proteasome activator complex subunit 1

Psme1

5.73/29

13/28

45

123

0.000015

3.57↓

COF1_MOUSE

Cofilin-1

Cfl1

8.22/19

7/9

34

96

0.00000032

9.36↓

COTL1_MOUSE

Coactosin-like protein

Cotl1

5.28/16

14/29

76

213

0.0000072

2.28↓

  1. *CyDye images were analyzed by BVA and spots that showed statistically significant differences (p<0.05) in intensity between the neonatal and the adult thymus groups are listed. pI: calculated isoelectric point; MW: nominal molecular weight;↑: up-regulated; ↓: down-regulated.