Pairwise protein overlap rates and hierarchical clustering of 21 samples based on protein pattern . A: Heatmap of the overlap rate between each sample pair. The higher overlap rates were clearly in the intra-gender region rather than in the inter-gender region. B: Hierarchical clustering of 21 samples also based on the protein overlap rates. The male/female samples clustered together. Both results showed that male and female urinary proteomes showed different patterns.