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Table 2 The estimated minimal sample number per group for quantitative analysis based on spectrum count method, where power is the power of statistical test, α is the significance level, and π refers to the estimated proportion of truly differentially expressed proteins among all of the identified proteins

From: An individual urinary proteome analysis in normal human beings to define the minimal sample number to represent the normal urinary proteome

fold change

power

α

π

FDR

normal group

male group

female group

2

0.8

0.001

0.05

2.31%

20

18

15

 

0.8

0.005

0.1

5.33%

16

14

12

 

0.8

0.01

0.2

4.76%

14

12

10

 

0.9

0.001

0.05

2.06%

24

22

17

 

0.9

0.005

0.1

4.76%

19

17

14

 

0.9

0.01

0.2

4.26%

17

15

12

1.5

0.8

0.001

0.05

2.31%

71

63

49

 

0.8

0.005

0.1

5.33%

56

49

39

 

0.8

0.01

0.2

4.76%

49

43

34

 

0.9

0.001

0.05

2.06%

87

77

60

 

0.9

0.005

0.1

4.76%

69

61

48

 

0.9

0.01

0.2

4.26%

62

54

43