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Table 2 The estimated minimal sample number per group for quantitative analysis based on spectrum count method, where power is the power of statistical test, α is the significance level, and π refers to the estimated proportion of truly differentially expressed proteins among all of the identified proteins

From: An individual urinary proteome analysis in normal human beings to define the minimal sample number to represent the normal urinary proteome

fold change power α π FDR normal group male group female group
2 0.8 0.001 0.05 2.31% 20 18 15
  0.8 0.005 0.1 5.33% 16 14 12
  0.8 0.01 0.2 4.76% 14 12 10
  0.9 0.001 0.05 2.06% 24 22 17
  0.9 0.005 0.1 4.76% 19 17 14
  0.9 0.01 0.2 4.26% 17 15 12
1.5 0.8 0.001 0.05 2.31% 71 63 49
  0.8 0.005 0.1 5.33% 56 49 39
  0.8 0.01 0.2 4.76% 49 43 34
  0.9 0.001 0.05 2.06% 87 77 60
  0.9 0.005 0.1 4.76% 69 61 48
  0.9 0.01 0.2 4.26% 62 54 43