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Table 2 Functional annotation clustering of identified cytokines using the DAVID database

From: An antibody microarray analysis of serum cytokines in neurodegenerative Parkinsonian syndromes

DAVID annotation cluster Enrichment score, p-value Associated Cytokines
1. Immune response, immunity and defense 7.28, p < 10-6 GRO, ICAM-1, MCP-4, IL-2RA, NAP-2, IL-6R, RANTES
2. Chemotaxis, taxis, locomotory behavior 6.64, p < 10-8 GRO, MCP-4, NAP-2, PDGF-BB, IL-6R, RANTES
3. Chemokine 4.23, p < 10-6 GRO, MCP-4, NAP-2, RANTES
4. Cell migration, leukocyte migration, cell motility 3.13, p < 10-5 ICAM-1, PDGF-BB, IL-6R, RANTES
5. Cell chemotaxis, response to steroid hormone stimulus 2.70, p < 10-4 PDGF-BB, IL-6R, RANTES
6. Regulation of cell migration, motion and locomotion 2.31, p < 0.01 ICAM-1, PDGF-BB, IL-6R
7. Response to hormone stimulus 2.24, p < 0.01 leptin, PDGF-BB, IL-6R, RANTES
8. Positive regulation of signal transduction 1.77, p < 0.05 leptin, IL6-R, prolactin
9. Diabetes type 2, metabolic disease, reproduction 1.63, p < 0.05 leptin, ICAM-1, IL-6R, RANTES