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Table 2 Functional annotation clustering of identified cytokines using the DAVID database

From: An antibody microarray analysis of serum cytokines in neurodegenerative Parkinsonian syndromes

DAVID annotation cluster

Enrichment score, p-value

Associated Cytokines

1. Immune response, immunity and defense

7.28, p < 10-6

GRO, ICAM-1, MCP-4, IL-2RA, NAP-2, IL-6R, RANTES

2. Chemotaxis, taxis, locomotory behavior

6.64, p < 10-8

GRO, MCP-4, NAP-2, PDGF-BB, IL-6R, RANTES

3. Chemokine

4.23, p < 10-6

GRO, MCP-4, NAP-2, RANTES

4. Cell migration, leukocyte migration, cell motility

3.13, p < 10-5

ICAM-1, PDGF-BB, IL-6R, RANTES

5. Cell chemotaxis, response to steroid hormone stimulus

2.70, p < 10-4

PDGF-BB, IL-6R, RANTES

6. Regulation of cell migration, motion and locomotion

2.31, p < 0.01

ICAM-1, PDGF-BB, IL-6R

7. Response to hormone stimulus

2.24, p < 0.01

leptin, PDGF-BB, IL-6R, RANTES

8. Positive regulation of signal transduction

1.77, p < 0.05

leptin, IL6-R, prolactin

9. Diabetes type 2, metabolic disease, reproduction

1.63, p < 0.05

leptin, ICAM-1, IL-6R, RANTES