Figure 8

Structure and mapped surfaces of 1kaz: The 3-D structure of a heat shock protein (PDB: 1kaz) is shown in the top-left, color-coded by electrostatic potential; negative, positive, and neutral regions are shown in blue, red, and white, respectively (image generated using Pymol [45]). Top right, bottom left, and bottom right figures show the 2-D map of the heat shock protein, enriched with hydrophobicity, electrostatic potential, and curvature information, respectively. Hydrophobic and hydrophilic regions are calculated using the Kyte-Doolittle scale are shown in red and blue, respectively. Convex and concave regions are shown in blue and white, respectively. The active site is denoted with a closed curve in each image.