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Table 1 Examples of overlapping clusters representing the same protein complex

From: Accuracy improvement in protein complex prediction from protein interaction networks by refining cluster overlaps

Prp19-associated complex

   complex :

YLL036C YMR213W YJR050W YLR117C YDR416W YGR129W YBR188C YPR101W

   cluster-1 :

YLL036C YDR416W YMR213W YGR129W YLR117C YNR011C YDR364C

   cluster-2 :

YLL036C YJR050W YDR416W YGR129W YLR117C YPL213W YIR009W

   cluster-3 :

YLL036C YDR416W YBR188C YGR129W YLR117C YPR101W

Set3p complex

   complex :

YGL194C YIL112W YDR155C YOL068C YKR029C YBR103W YCR033W

   cluster-1:

YGL194C YKR029C YCR033W YIL112W

   cluster-2 :

YGL194C YKR029C YBR103W

cAMP-dependent protein kinase

   complex :

YIL033C YJL164C YPL203W YKL166C

   cluster-1 :

YNL227C YKL166C YPL203W

   cluster-2 :

YIL033C YPL203W

NuA4 histone acetyltransferase complex

   complex :

YFL039C YJL081C YPR023C YEL018W YJR082C YNL136W YFL024C YOR244W YGR002C YHR099W YDR359C YNL107W YHR090C

   cluster-1 :

YNL107W YOR244W YFL024C YPR023C

   cluster-2 :

YJL081C YFL024C

RAVE complex

   complex :

YJR033C YDR202C YDR328C

   cluster-1 :

YDR306C YDR202C YJL204C YGL149W YOR080W YJL149W YMR258C YBR280C YJR033C YML088W YDR131C YLR368W YLR097C YDL132W YLR352W YDR328C YLR224W

   cluster-2 :

YMR054W YJR033C YDR202C YOR270C YBR127C YDL185W YHR060W

  1. We applied the entropy-based approach to the yeast protein interaction network. For each cluster, we computed f-scores by comparing to experimentally determined protein complexes and chose one complex with the highest f-score. It shows five examples that two or more clusters have the highest f-score to the same protein complex.
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Proteome Science

ISSN: 1477-5956