Figure 2
From: HopDock: a probabilistic search algorithm for decoy sampling in protein-protein docking
Overview of Basin Hopping Framework. Under the BH framework, the energy surface is transformed into a collection of interpenetrating staircases. A trajectory of local minima is obtained consecutively, through iterated applications of a structural perturbation to jump out of a current local minimum and an ensuing local optimization to map to another nearby local minimum.
