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Figure 4 | Proteome Science

Figure 4

From: Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes

Figure 4

Spatial organization of cell migration related signalling pathways in the three cell migration modes. (A,B) Histogram (black) of the coverage (x100%) of cell migration related pathways, ranked in descending order based on the proteomic and phospho-proteomic data sets. For every pathway the absolute number of proteins contained in the data is illustrated with thinner red bars. The level of absolute overlap of subsequent pathways is illustrated with horizontal green segments connecting the red bars. The list of the canonical pathways is indicated on every figure. (C,D) Heatmaps of enrichment for the relevant canonical pathways of the proteomic and phospho-proteomic data sets. The pathway names are listed according to descending pathway coverage, and their names correspond exactly to the numbering of panels A and B. The logarithmic ratio of number of proteins found in each enrichment range, and for every cell migration mode, to the total number of proteins in the data for this pathway, is indicated by a colour map which ranges from green to red. Green corresponds to no proteins and red to all the proteins of this pathway.

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