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Figure 4 | Proteome Science

Figure 4

From: Assessment of vascular endothelial growth factor in formalin fixed, paraffin embedded colon cancer specimens by means of a well-based reverse phase protein array

Figure 4

Reliability of well-based RPPA and its correlation with immunohistochemistry. Scatter diagrams are presented by unnormalized VEGF value vs. immunohistochemical VEGF score (A) and normalized VEGF value vs. IHC VEGF score (B). There was a statistically meaningful correlation between expressional signals in the normalized VEGF value by well-based RPPA and immunohistochemical VEGF score (r = 0.283, P = 0.018) whereas the unormalized VEGF signal was expressed negative correlation (r = -0.350, P = 0.003). By histologic subgroup analysis, adenocarcinoma type (C) was only showed good correlation (r = 0.315, P = 0.031) with IHC assessment compare to that of mucinous adenocarcinoma (r = -0.086, P = 0.703, D).

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