Inflammation: an important parameter in the search of prostate cancer biomarkers

Table 6 Differentially expressed proteins in BPH without inflammation vs BPH with inflammation

Spot n°.	Acc. n°.	Protein full name	Mass (Da)	Score	N° matchs/signif. matchs	N° seq./signif. seq.	Expression change
D1	P00751	Complement factor B	86847	501	196/57	34/15	↑
D2	P06396	Gelsolin	86043	301	141/37	25/14	↑
D3	P00734	Prothrombin	71475	168	42/14	12/5	↑
D4	P02749	Beta-2-glycoprotein 1	39584	39	15/2	5/2	↑
D5	P02749	Beta-2-glycoprotein 1	39584	41	32/15	7/4	↑
D6	P02749	Beta-2-glycoprotein 1	39584	331	72/30	13/9	↑
D7	P02749	Beta-2-glycoprotein 1	39584	204	70/33	13/7	↑
D8	P02774	Vitamin-D binding protein	54526	1679	283/149	32/28	↑
D9	P01011	Alpha-1-antichymotrypsin	47792	324	54/24	11/8	↑
D10	P02765	Alpha-2-HS-glycoprotein	40098	273	96/38	11/9	↑
D11	P01024	Complement C3 (fragment)	188569	700	210/73	33/16	↑
D12	P01024	Complement C3 (fragment)	188569	1500	300/126	42/23	↑
D13	P25311	Zinc-alpha-2-glycoprotein	34465	66	15/6	6/3	↑
D14	P10909	Clusterin	53031	83	21/4	8/2	↑
D15	P10909	Clusterin	53031	245	42/14	8/4	↑
D16	P10909	Clusterin	53031	159	39/14	8/6	↑
D17	P10909	Clusterin	53031	174	25/11	6/3	↑
D18	P01024	Complement C3 fragment	188569	834	119/57	16/10	↑
D19	P02753	Retinol binding protein 4	23337	585	134/64	9/9	↑
D20	P02656	Apolipoprotein C-III	10846	231	7/7	2/2	↑
D21	P00738	Haptoglobin	45861	524	102/43	15/10	↓
D22	P00738	Haptoglobin	45861	348	90/34	17/9	↓
D23	Q14624	Inter-alpha-trypsin inhibitor heavy chain H4	103521	222	30/19	7/6	↓
D24	P0DJI8	Serum amyloid A-1 protein	13581	269	26/13	10/5	↓
D25	P0DJI8	Serum amyloid A-1 protein	13581	360	29/16	10/5	↓

Protein names in italic: proteins found also in the comparison between PCa without inflammation and PCa with inflammation (Table 5).

ISSN: 1477-5956