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Table 4 Functional classification of dysregulated proteins in mild cognitive impairment and Alzheimer’s disease using DAVID bioinformatics tool

From: Plasma protein profiling of Mild Cognitive Impairment and Alzheimer’s disease using iTRAQ quantitative proteomics

  

Enrichment score¶

Protein count

P value

Benjamin

Biological process

Acute inflammatory response

9.6

8

2.5E-11

6.1E-9

Blood coagulation

4.19

4

3.1E-4

5.2E-3

Cell activation

4.19

4

1.6E-2

3.3E-2

Lipid transport

3.35

5

3.4E-5

1.7E-3

Complement activation

2.45

3

6.6E-4

8.9E-3

Molecular function

Enzyme inhibitor activity

6.66

8

1.5E-8

3.5E-7

Cell surface binding

4.19

5

3.6E-8

5.0E-7

Enzyme activator activity

3.35

4

7.4E-3

3.7E-2

Sterol transporter activity

3.35

3

1.3E-4

9.0E-4

 

Unclassified

 

7

  
  1. ¶The full human genome was used as the reference list [21, 22]. The classification stringency was set to medium.
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Proteome Science

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