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Table 5 Comparison of average disease/normal iTRAQ ratios for apolipoproteins on pooled plasma with individual samples assayed by ELISA multiplex assays

From: Plasma protein profiling of Mild Cognitive Impairment and Alzheimer’s disease using iTRAQ quantitative proteomics

iTRAQ*

Multiplex assay§

 

aMCI:Normal

nMCI:Normal

AD:Normal

MCI:Normal

ApoA1

0.85

0.96

1.07

0.91

ApoA2

0.78

0.93

0.88

0.94

ApoB

1.02

1.18

1.01

1.06

ApoH

0.99

0.96

0.98

0.91

ApoJ

0.94

1.10

1.07

1.10

  1. *average ratios of three iTRAQ replicates.
  2. §ratios of the mean values of apolipoprotein levels assayed in MCI and Normal groups using individual plasma samples, as detailed in Song et al.[12].
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Proteome Science

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