Table 1 Differentially expressed peptides/proteins from gills (A) and digestive gland (DG, B) of Blue mussels obtained from controls (C) and 21d exposures to 0.5 mg/L crude oil (oil) and 0.5 mg/L crude oil spiked with a mixture of APs and PAHs (0.1 mg/L; sO); mean intensities (arbitrary values) and SD of controls (Gills, n = 51; DG, n = 74), oil (Gills, n = 66; DG, n = 71) and sO (Gills, n = 55; DG, n = 69). Expression changes relative to the controls are significantly different at a level of p < 0.001 (one-way ANOVA for C vs. oil vs. sO) at least for one of the exposures. Peaks are listed in decreasing order of their respective p values from top to bottom.

C

oil

sO

Down-regulation

14847

1.01 ± 0.32

0.61 ± 0.26

0.81 ± 0.31

6696

2.76 ± 1.19

1.86 ± 1.34

1.64 ± 1.33

9661

8.11 ± 3.82

5.35 ± 3.63

8.35 ± 5.06

Up-regulation

7811

0.83 ± 0.74

1.46 ± 1.22

2.76 ± 1.84

16196

0.75 ± 1.20

1.23 ± 1.46

2.18 ± 2.06

4744

0.43 ± 1.05

0.65 ± 1.60

1.37 ± 1.80

3795

0.84 ± 1.42

1.33 ± 2.19

2.64 ± 3.39

3984

1.04 ± 2.03

1.04 ± 1.97

2.67 ± 3.05

4108

0.49 ± 1.36

0.44 ± 1.32

1.34 ± 1.95

3552

0.69 ± 2.00

0.54 ± 1.34

1.67 ± 2.66

28764

0.76 ± 0.7 7

1.78 ± 1.45

1.76 ± 1.23

52306

0.34 ± 0.25

0.72 ± 0.73

0.46 ± 0.44

Down-regulation

9172

3.78 ± 4.26

2.46 ± 2.21

1.01 ± 0.86

18250

0.47 ± 0.40

0.23 ± 0.26

0.15 ± 0.17

7410

1.09 ± 0.59

0.74 ± 0.57

0.55 ± 0.32