Proteomic analysis of tyrosine phosphorylation during human liver transplantation

Table 1 Anti-PY binding proteins – 60 min ischemia

Protein name	Accession number^¶	Mascot score	Sequence Coverage	Peptide number	Subellular Localization	Biological Function	Reported PY sites*	Predicted PY sites+
Serum albumin precursor	P02768	410	22%	10	secreted	transport	none	108, 164, 365, 476, 521
Carbamoyl-phosphate synthetase 1	Q5R206	298	4%	5	mitochondrion	detoxification	none	443, 634, 768, 852, 872, 957, 959, 1032, 1305, 1450
Dihydrolipoamide branched chain transacylase	P11182	196	14%	6	mitochondrion	energy metabolism	none	36, 85, 130
Nck adaptor protein 1	P16333	164	11%	4	cytosol	signalling	none	13, 112, 268, 339
Phosphoenolpyruvate carboxykinase	P35558	70	2%	1	mitochondrion	energy metabolism	none	165, 279, 595
Enoyl-CoA hydratase	P30084	62	2%	1	mitochondrion	energy metabolism	none	35
Alcohol dehydrogenase [NADP+]	P14550	47	4%	2	cytosol	detoxification	none	49, 139, 240, 324

Proteins identified in the 60 min ischemia and the 60 min reperfusion fractions are represented in italic.
^¶ Database: SwissProt
*source: SwissProt and Human Protein Reference Database
⁺ source: NetPhos 2.0

ISSN: 1477-5956