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Table 1 Anti-PY binding proteins – 60 min ischemia

From: Proteomic analysis of tyrosine phosphorylation during human liver transplantation

Protein name Accession number Mascot score Sequence Coverage Peptide number Subellular Localization Biological Function Reported PY sites* Predicted PY sites+
Serum albumin precursor P02768 410 22% 10 secreted transport none 108, 164, 365, 476, 521
Carbamoyl-phosphate synthetase 1 Q5R206 298 4% 5 mitochondrion detoxification none 443, 634, 768, 852, 872, 957, 959, 1032, 1305, 1450
Dihydrolipoamide branched chain transacylase P11182 196 14% 6 mitochondrion energy metabolism none 36, 85, 130
Nck adaptor protein 1 P16333 164 11% 4 cytosol signalling none 13, 112, 268, 339
Phosphoenolpyruvate carboxykinase P35558 70 2% 1 mitochondrion energy metabolism none 165, 279, 595
Enoyl-CoA hydratase P30084 62 2% 1 mitochondrion energy metabolism none 35
Alcohol dehydrogenase [NADP+] P14550 47 4% 2 cytosol detoxification none 49, 139, 240, 324
  1. Proteins identified in the 60 min ischemia and the 60 min reperfusion fractions are represented in italic.
  2. Database: SwissProt
  3. *source: SwissProt and Human Protein Reference Database
  4. + source: NetPhos 2.0