From: Proteomic analysis of plasma membrane and secretory vesicles from human neutrophils
Plasma membrane vesicles | Secretory vesicles |
---|---|
Adhesion | |
Integrin alpha-M (CD11b) Integrin beta-2 (CD18 antigen) Integrin alpha-IIb Intercellular adhesion molecule-3 (ICAM-3) Phagocytic glycoprotein I (CD44 antigen) | Integrin alpha-M (CD11b) Integrin beta-2 (CD18 antigen) ADP-ribosyl cyclase 2 (CD157 antigen) Erythrocyte band 7 integral membrane protein (Stomatin) |
Cytoskeletal | |
Beta-actin (ACTB) Alpha-actinin 1 Alpha-actinin 4 Cofilin, non-muscle form Coronin-1A Moesin Myosin light polypeptide 6 Myosin regulatory light chain 2, nonsarcomeric Tropomyosin alpha 3 chain Tropomyosin beta chain | Beta-actin (ACTB) Myosin-9 Tubulin alpha-ubiquitous chain |
Signal transduction | |
Guanine nucleotide-binding protein G(i), alpha-2 subunit Tyrosine protein kinase Lyn * Flotillin* B-cell receptor-associated protein 31 Chloride intracellular channel protein 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 HLA class I histocompatibility antigen, A-26 alpha chain Interferon-induced transmembrane protein 1 Ras-related protein Rap-1A Ras-related protein Rab-5A Ras-related protein Rap-1b Ras-related protein Rab-27B Synaptosomal-associated protein 23 | Guanine nucleotide-binding protein G(i), alpha-2 subunit Tyrosine protein kinase Lyn * Flotillin* Adipocyte plasma membrane-associated protein C5a anaphylatoxin chemotactic receptor Dysferlin Leukocyte surface antigen CD47 5-lipoxygenase activating protein (FLAP) Solute carrier family 2, facilitated glucose transporter, member 3 |
NADPH oxidase | |
Cytochrome b-245 heavy chain (gp91phox )* | Cytochrome b-245 heavy chain (gp91phox) |
Differentiation | |
 | Myeloid-associated differentiation marker (SB135) Leukocyte common antigen (CD45 antigen) |
Serum protein | |
Serum albumin | Serum albumin Alpha-1-antitrypsin Ig gamma-1 chain C region |
Mitochondrial/Microsomal | |
 | ATP synthase alpha chain, mitochondrial ATP synthase beta chain, mitochondrial Citrate synthase, mitochondrial Cytochrome P450 4F2 60 kDa heat shock protein, mitochondrial (Hsp60) Isocitrate dehydrogenase [NADP], mitochondrial Malate dehydrogenase, mitochondrial Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sulfide: quinone oxidoreductase, mitochondrial Trifunctional enzyme beta subunit, mitochondrial Vacuolar ATP synthase subunit d |
Metabolic | |
 | Aldehyde dehydrogenase 3B2 Dehydrogenase/reductase SDR family member 7 Tyrosine-protein phosphatase non-receptor type substrate 1 |
Granule | |
Lactoferrin Matrix metalloproteinase 9 Myeloperoxidase Cathepsin G Azurocidin | Lactoferrin Matrix metalloproteinase 9 Myeloperoxidase Aminopeptidase N (CD13 antigen) Eosinophil peroxidase |
Cytosolic | |
14-3-3 protein zeta/delta | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48 kDa subunit |
Unknown | |
Actin-related protein 2 Golgi-associated plant pathogenesis related protein 1 Protein FAM49B Tetratricopeptide repeat protein 10 | ERO1-like protein alpha Pantophysin |