Figure 1

Diagnostic plot generated from a Pearson correlation matrix of 66 QC spectra from the CMLS-F4 data set. A cut-off value of 1-Mean of Pearson correlation coefficient > 0.2 was used to exclude spectra from the QC analysis (blue line). In this data set, 2 QC sample spectra were above this cut-off (colored blue) and therefore were removed prior to further processing. For spectra from the investigational data set, a 1-Mean > 0.4 was used for all ProteinChip-Fraction combinations.