Figure 3

Fingerprints HDL, HDL deficient plasma, LDL and VLDL. All particles were first isolated by gel filtration were subjected to SELDI-TOF analysis according to the methods as described in the M&M section. Upper and Second panel: A spectrum of HDL from a normal subject and HDL deficient plasma (Tangier patient having virtually no HDL cholesterol [29]). Insert: The cholesterol gel filtration profile of HDL deficient plasma showing only the presence of VLDL and LDL and no lipid containing HDL. Third and lower panel: LDL and VLDL spectra showing virtually no HDL specific pattern.