Table 1 Subset of age-associated proteins from quantitative proteomic analysis of liver peroxisomal proteins. Proteins were identified by MALDI-TOF MS ^a).

A (Fold)

SDV(Fold)

B (Fold)

SDV(Fold)

C (Fold)

SDV(Fold)

Pathway

Location

NCBI nr

Cvage

Score

p

Mr ob

pI ob

1

0.29

-2.12

0.03

1.63

0.22

β-oxidation

pero

gi|66793429

24%

60

0.1

25000

9

1

0.31

-1.62

0.47

3.11

0.52

β-oxidation

pero

giI30525893

26%

66

0.0251189

40000

9.0

1

0.48

0.00

0.00

2.20

0.52

α-oxidation

pero

gi|31560355

30%

104

3.981E-06

65000

6.8

1

0.15

-1.48

0.34

-3.28

0.06

isoprenoid biosynthesis

pero

gi|20965433

33%

68

0.0158489

26000

8.7

1

0.50

-1.31

0.39

2.05

0.69

isoprenoid biosynthesis related

pero

gi|409499

24%

70

0.01

33000

9.1

1

0.42

2.78

0.43

1.48

0.23

amino acid metabolism

pero

gi|19388006

24%

63

0.0501187

42000

7.8

1

0.09

1.02

0.25

-3.77

0.13

putative peroxisomal prot

pero

gi|6678726

18%

60

0.1

67000

6.1

1

0.43

2.14

0.39

-1.09

0.41

putative peroxisomal prot

pero

gi|6753036

40%

117

1.995E-07

60000

6.6

1

0.18

-1.33

0.10

-2.87

0.13

β-oxidation

mito

gi|21431780

24%

55

0.3162278

33000

8.8

1

0.21

0.00

0.00

9.36

0.15

β-oxidation

mito

gi|20810027

23%

70

0.01

46000

7.8

1

0.14

2.26

0.62

1.09

0.29

glutamate biosynthesis

mito

gi|6680027

22%

64

0.0398107

60000

7.4–7.5

1

0.38

-1.20

0.15

-3.31

0.21

stress response

mito

gi|14917005

25%

63

0.0501187

75000

6.2

1

0.32

2.52

0.53

1.32

0.38

glutamine metabolism

cyt

gi|15419027

28%

59

0.1258925

42000

7.5

1

0.05

7.35

0.46

0.00

0.00

protein folding

cyt

gi|129729

28%

64

0.0398107

61000

5