Table 2 Subset of age-associated proteins from quantitative proteomic analysis of kidney peroxisomal proteins. Proteins were identified by MALDI-TOF MS a).
From: Age-related subproteomic analysis of mouse liver and kidney peroxisomes
10 wks | 18 mns | 24 mns | Â | Â | Â | Â | Â | Â | Â | Â | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D (Fold) | SDV(Fold) | E (Fold) | SDV(Fold) | F (Fold) | SDV(Fold) | Pathway | Location | NCBI nr | Cvage | Score | p | Mr ob | pI ob |
1 | 0.22 | -3.4 | 0.04 | 1.02 | 0.06 | auxiliary β-oxidation | pero | gi|6753272 | 30% | 114 | 3.981E-07 | 60000 | 7.5–7.8 |
1 | 0.18 | -2.27 | 0.02 | 1.04 | 0.12 | auxiliary β-oxidation | pero | gi|6753272 | 30% | 114 | 3.981E-07 | 60000 | 7.5–7.8 |
1 | 0.31 | -4.16 | 0.07 | -1.86 | 0.10 | β-oxidation | pero | gi|66793429 | 24% | 60 | 0.1 | 25000 | 9 |
1 | 0.16 | -1.18 | 0.46 | -3.53 | 0.13 | β-oxidation | pero | giI30525893 | 26% | 66 | 0.0251189 | 40000 | 9.0 |
1 | 0.26 | 0 | 0.00 | -4.38 | 0.35 | α-oxidation | pero | gi|6754564 | 20% | 64 | 0.0398107 | 36000 | 7.3 |
1 | 0.12 | 0 | 0.00 | -1.44 | 0.22 | α-oxidation | pero | gi|31560355 | 30% | 104 | 3.981E-06 | 65000 | 6.8 |
1 | 0.29 | 3.04 | 0.58 | -1.73 | 0.05 | isoprenoid biosynthesis | pero | gi|20965433 | 33% | 68 | 0.0158489 | 26000 | 8.7 |
1 | 0.18 | -1.11 | 0.22 | -2.61 | 0.15 | isoprenoid biosynthesis related | pero | gi|409499 | 24% | 70 | 0.01 | 33000 | 9.1 |
1 | 0.14 | 0 | 0.00 | 6.80 | 1.10 | amino acid metabolism | pero | gi|19388006 | 24% | 63 | 0.0501187 | 42000 | 7.8 |
1 | 0.17 | 4.6 | 0.36 | 0.00 | 0.00 | amino acid metobolism | pero | giI17390882 | 25% | 65 | 0.0316228 | 33000 | 6.0 |
1 | 0.10 | -1.95 | 0.16 | 0.00 | 0.00 | amino acid metobolism | pero | gi|477004 | 32% | 104 | 3.981E-06 | 65000 | 6.5 |
1 | 0.27 | -2.88 | 0.14 | 1.14 | 0.19 | amino acid metobolism | pero | gi|477004 | 32% | 104 | 3.981E-06 | 65000 | 6.7 |
1 | 0.23 | 1.24 | 0.05 | -1.59 | 0.15 | purine/pyrimidine metabolism | pero | gi|18044669 | 26% | 63 | 0.0501187 | 35000 | 9.0–9.1 |
1 | 0.27 | 3.45 | 0.52 | -1.21 | 0.13 | putative peroxisomal protein | pero/cyt | gi|226778 | 24% | 67 | 0.0199526 | 33000 | 7.5 |
1 | 0.19 | 2.46 | 0.45 | 0.00 | 0.00 | putative peroxisomal protein | pero | gi|76779273 | 21% | 59 | 0.1258925 | 62000 | 5.7–5.9 |
1 | 0.14 | 1.94 | 0.22 | -1.17 | 0.37 | β-oxidation | cyt | gi|13182962 | 39% | 60 | 0.1 | 30000 | 9.0 |
1 | 0.14 | 10.66 | 0.10 | 0.00 | 0.00 | β-oxidation | mito | gi|21431780 | 24% | 55 | 0.3162278 | 33000 | 8.8 |
1 | 0.18 | 4.3 | 0.17 | 0.00 | 0.00 | β-oxidation | mito | gi|26345684 | 25% | 67 | 0.0199526 | 45000 | 6.5 |
1 | 0.19 | 4.26 | 0.62 | 3.58 | 0.63 | glycolysis | mito | gi|18043470 | 24% | 54 | 0.3981072 | 37000 | 6.1 |
1 | 0.24 | 3.61 | 0.71 | 0.00 | 0.00 | stress response | mito | gi|14917005 | 25% | 63 | 0.0501187 | 75000 | 6.0 |
1 | 0.20 | 3.06 | 0.22 | 1.37 | 0.43 | stress response | mito | gi|14917005 | 25% | 63 | 0.0501187 | 75000 | 6.2 |