From: Proteome alteration induced by hTERT transfection of human fibroblast cells
 |  |  |  | hTERTt-WI38/WI38 | hTERT-WI38/HPV-WI38 | ||
---|---|---|---|---|---|---|---|
Swiss-Prot AC | Gene name, STRING protein association network legend | Protein name | Function | T-test | Regulation | T-test | Regulation |
[P31943] | HNRPH1 | Heterogeneous nuclear ribonucleoprotein H | Pre-mRNAs processing | 4.4E-03 | 1.73 | 3.0E-02 | 1.58 |
[P08235] | NR3C2 | Mineralocorticoid receptor | Binds to mineralocorticoid response elements (MRE) and transactivates target genes | 6.1E-03 | 1.65 | 1.6E-02 | 1.53 |
[O14579] | COPE | Coatomer subunit epsilon | Implicated in vesicles trafficking | 4.2E-02 | 1.62 | 0.12 | 1.33 |
[Q05048] | CSTF1 | Cleavage stimulation factor 50 kDa subunit | Polyadenylation and 3'-end cleavage of mammalian pre-mRNAs | 1.5E-03 | 1.57 | 5.6E-03 | 1.64 |
[P07900] | HSPCA | Heat shock protein HSP 90-alpha | Chaperone, 680kDa human telomerase complex partner [72] | 1.5E-02 | 1.42 | 2.2E-04 | 2.05 |
[P62826] | ARA24 | GTP-binding nuclear protein Ran | nucleocytoplasmic transport | 2.0E-02 | 1.37 | 6.7E-03 | 1.24 |
[O43809] | ENSP0000030 0291 | Cleavage and polyadenylation specificity factor 5 | Polyadenylation and 3'-end cleavage of mammalian pre-mRNAs | 1.6E-02 | 1.35 | - | 1.35 |
[Q13838] | ATP6V1G2 | splicesome RNA helicase BAT1 | Splice factor, required for mRNA export | 6.3E-03 | 1.34 | 1.7E-03 | 1.5 |
[P25788] | PSMA3 | Proteasome subunit alpha type 3 | Protein degradation | 5.6E-03 | 0.68 | 4.7E-02 | 0.75 |
[P28072] | PSMB6 | Proteasome subunit beta type 6 precursor | Protein degradation | 3.8E-05 | 0.65 | 3.0E-04 | 0.66 |
[P08865] | RPSA | 40S ribosomal protein SA | Protein synthesis | 1.3E-04 | 0.58 | 5.4E-04 | 0.60 |
[P60842] | EIF4A1 | Eukaryotic initiation factor 4A-I | RNA helicase which mediates binding of mRNA to the ribosome | 3.1E-02 | 0.54 | 1.2E-01 | 0.52 |
[P09382] | LGALS1 | Galectin-1 | Cell growth, apoptosis and cell differentiation | 8.8E-07 | 0.50 | 1.2E-06 | 0.51 |
[Q12906] | ILF3 | Interleukin enhancer-binding factor 3 | Translation inhibitory protein of acid beta-glucosidase and other mRNAs, IL2 transcription regulator, promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA | 1.1E-05 | 0.47 | 9.5E-04 | 0.66 |