Proteomic changes in rat hippocampus and adrenals following short-term sleep deprivation

Table 1 Hippocampal proteins whose abundance differs between conditions with protein ID from Swiss Prot database, analysis and identification information.

Master #	Protein ID	Name	Function	Average ratio	p-value	pI	Mw	Mowse score
1169	AINX_RAT	α-internexin	Y	-1.52	0.000082	5.2	56253	108
1166	DPYL2_RAT	Dihydropyrimidinase-related protein 2	D	-1.64	0.012	5.95	62638	100
1192	GDIA_RAT	Rab GDI α	G	-1.31	0.045	5	51074	100
1489	GFAP_RAT	Glial fibrillary acidic protein	Y	-1.35	0.04	5.35	49970	90
1781	KCRB_RAT	Creatine kinase type B	M	-1.26	0.045	5.33	42970	236
971	NSF_MOUSE	Vesicle fusing ATPase	T	-1.33	0.0067	6.52	83083	68
1753	NDUS2_MOUSE	NADH ubiquinone oxidoreductase	M	-1.22	0.012	6.52	52991	69
1230	PDIA3_RAT	Protein disulfide isomerase A3	C	1.83	0.033	5.88	57044	100
1869	PURA_MOUSE	Transcriptional activator protein Pur-α	A	-1.23	0.025	6.07	34976	54
2462	SNAA_RAT	α-soluble NSF attachment protein	T	-1.37	0.017	5.3	33627	107
1131	TPMT_CANFA	Thiopurine S-methyltransferase	C	-1.42	0.0071	6.46	28752	87
532	YPEL4_RAT	Protein yippee-like 4	?	1.53	0.036	8.42	14762	44

In the Function column, A = transcriptional regulation, C = protein translation, folding and degradation, D = development, G = cell signalling, M = cell metabolism and energy, S = stress, chaperone, T = transport and vesicle trafficking, Y = cytoskeleton. In the Average ratio column, a negative number corresponds to a protein more abundant after 4 hours of sleep deprivation than 4 hours of sleep. The average ratio represents the ratio between the average protein abundances in the different conditions (n = 6), as computed by the DeCyder software. Other abbreviations: pI = identified isoelectric point ; Mw = identified molecular weight. Mowse score as defined by Pappin et al. [62]

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