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Table 2 Cancer associated MALDI/SELDI peaks.

From: Proteomic profiling of urine for the detection of colon cancer

Method

m/z

P value (t-test)

P value (LM)

Fold change

AUROC

MALDI

1606*

0.0001

0.0006

0.72

0.71

MALDI

2051*

0.0253

0.0338

1.20

0.64

MALDI

2195*

0.0027

0.0373

0.67

0.65

MALDI

2254*

0.0023

0.0030

1.24

0.69

MALDI

4169*

0.0074

0.0083

1.25

0.65

MALDI

5011

0.0068

0.0009

1.23

0.68

MALDI

5239*

0.0009

0.0002

1.31

0.68

MALDI

11025*

0.0186

0.0430

0.48

0.60

MALDI

11400*

0.0146

0.0133

0.44

0.59

MALDI-DS

2193*

0.0001

0.0001

0.53

0.70

MALDI-DS

2758*

0.0029

0.0029

0.74

0.64

MALDI-DS

4758*

0.0121

0.0408

0.70

0.64

MALDI-DS

5812*

0.0052

0.0070

0.59

0.63

MALDI-DS

6250

0.0426

0.0108

1.22

0.60

SELDI

1885

0.0153

0.0450

1.28

0.64

SELDI

6086*

0.0259

0.0050

1.14

0.61

SELDI

11750*

0.0019

0.0032

1.67

0.67

SELDI

11960*

0.0005

0.0182

1.65

0.68

SELDI-HR

39480

0.0217

0.043

0.94

0.62

SELDI-HR

53760*

0.0293

0.0150

0.98

0.64

  1. Table 2 shows the m/z ratios, p-values obtained by t-test and multiple linear regression (LM), fold-change (cancer mean intensity/control mean intensity) and area under the receiver operator characteristic curve (AUROC) for all peaks which obtained p < 0.05 in both statistical tests. The peaks that are significant in one or both statistical tests if only the early stage cancers are compared to the non-cancer controls are marked with an asterisk.