Figure 2
From: The identification of disease-induced biomarkers in the urine of BSE infected cattle
Principle component analysis of the 8 biological replicates. The samples obtained from individual infected and control cows clustered together indicating that disease is the factor that most influences the differential abundance observed in the urine samples. The time of the 6 sample collections from cow #54 are given to illustrate that the urine proteome of this animal diverged further from all the other animals as the disease progressed. This analysis was based on the 36 spot features exhibiting statistically significant (ANOVA p < 0.01) changes in abundance and present on all 46 gel images. (PC1 = 36.3, PC2 = 15.2).