A proteomic approach identified growth hormone-dependent nutrition markers in children with idiopathic short stature

Table 2 The most predictive peaks identified by rotated two-component PLS regression analysis.

Number of peaks	R²	CVcorrect	First year growth hormone responsiveness Peak m/z value (kDa)
15	0.51	64	17.584, 17.383, 17.256, 17.139, 13.788, 9.127, 8.820, 8.689, 6.833, 6.626, 6.474, 6.428, 4.401, 3.212 and 3.311
5	0.47	76	13.877, 17.139, 17.256, 17.584 and 6.428
4	0.47	78	13.877, 17.139, 17.256 and 17.584
3	0.47	81	13.877, 17.139 and 17.256
2	0.47	82	13.877 and 17.139
			Before treatment
15	0.32	59	3.311, 4.401, 4.463, 7.010, 8.689, 8.820, 9.709, 13.877, 14.040, 14.142, 15.132, 17.139, 17.256, 17.584, 28.067
5	0.23	63	14.040, 14.142, 17.139, 17.256, 28.067
4	0.24	65	14.142, 17.139, 17.256, 28.067
3	0.32	74	9.361, 14.040, 17.256
2	0.17	59	17.139, 17.256

The most predictive peaks identified by rotated two-component PLS regression analysis when 2, 3, 4, 5 and 15 peaks were included in the analysis. For each model the R²-value and correct rate of classification (CVcorrect) are presented. It is the peak intensity changes during the first year of GH treatment that are used in the analyses.

ISSN: 1477-5956