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Table 2 Proteins involved in redox balance

From: The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

   Normalized Volumes
Mean (SD)
WTFA vs WTO3
p ≤ 0.05
Normalized Volumes
Mean (SD)
KOFA vs KOO3
p ≤ 0.05
WTFA vs KOFA
p ≤ 0.05
WTO3 vs KOO3
p ≤ 0.05
   WTFA WTO3   KOFA KOO3    
Aldehyde dehydrogenase AHD-M1 1.24
(0.163)
0.93
(0.286)
  1.23
(0.163)
0.86
(0.140)
*   
Aldehyde dehydrogenase
(EC 1.2.1.5)
2.75
(0.471)
1.83
(0.570)
* 2.57
(0.365)
1.68
(0.362)
*   
Aldose reductase
(EC 1.1.1.21)
1.84
(0.193)
1.60
(0.294)
  1.88
(0.362)
1.53
(0.348)
   
Apolipoprotein A-I 1.59
(0.300)
2.18
(0.350)
* 2.24
(0.668)
4.41
(1.038)
*   *
Apolipooprolein A-IV 2.50
(0.221)
3.01
(0.306)
* 2.69
(0.122)
3.27
(0.611)
   
Carbonyl reductase 2 4.47
(0.537)
2.66
(1.329)
* 4.67
(0.543)
2.36
(0.453)
*   
Ceruloplasmin isoform 7.51
(0.766)
9.48
(1.487)
.056 7.53
(0.960)
9.39
(1.337)
.065   
Cytosolic malate dehydrogenase 1.18
(0.126)
0.80
(0.234)
* 1.09
(0.141)
0.80
(0.124)
*   
Ferritin light chain 1.43
(0.325)
1.21
(0.180)
  1.34
(0.382)
1.13
(0.380)
   
Gelsolin 7.07
(1.072)
11.69
(3.636)
.051 6.87
(0.347)
11.89
(1.682)
*   
Glutathione S-transferase A4 (GST A4-4) 1.41
(0.153)
0.80
(0.445)
* 1.32
(0.148)
0.65
(0.146)
*   
Glutathione S-transferase omega 1 3.52
(0.140)
2.78
(0.416)
* 2.94
(0.422)
2.77
(0.986)
  *  
Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) 2.54
(0.750)
1.94
(1.125)
  1.99
(0.379)
1.48
(0.241)
.067   
Heat shock protein 70 3.93
(0.807)
5.82
(1.173)
* 4.64
(0.556)
7.79
(1.026)
*   *
Hemopexin 9.19
(1.184)
10.85
(1.000)
.076 11.49
(0.759)
13.71
(0.905)
* * *
Isocitrate dehydrogenase cytoplasmic (EC 1.1.1.42) 2.14
(0.119)
2.12
(0.152)
  1.64
(0.241)
1.97
(0.662)
  *  
Lactate dehydrogenase 2,
B chain
1.26
(0.417)
1.03
(0.520)
* 1.05
(0.179)
0.84
(0.062)
.072   
Peroxiredoxin 6 (Antioxidant protein 2; AOP2) 5.60
(0.884)
3.35
(1.694)
.057 5.39
(0.486)
3.11
(0.667)
*   
Protein disulfide-isomerase A3 (EC 5.3.4.1) 5.62
(1.658)
4.87
(1.685)
  4.67
(0.956)
4.64
(0.211)
   
Retinal dehydrogenase (RALDH1)(EC 1.2.1.36) 7.88
(1.629)
5.55
(1.817)
  7.85
(1.118)
5.07
(1.220)
*   
Selenium binding protein 1 1.42
(0.177)
0.83
(0.402)
* 1.39
(0.212)
0.68
(0.105)
*   
Selenium binding protein 2 5.61
(0.794)
3.53
(1.407)
* 5.33
(0.742)
3.00
(0.472)
*   
  1. The proteins assigned to the redox balance category (RED) are listed (n = 22). An arrow indicates whether levels of expression are increased (↑) or decreased (↓) in response to ozone. The mean values for the normalized volumes and standard deviations for each named protein are given for WTFA, WTO3, KOFA, and KOO3. The asterisk indicates whether the p-value for the comparisons of WTFA vs. WTO3; KOFA vs. KOO3; WTFA vs. KOFA; and WTO3 vs. KOO3 was ≤ 0.05. Values that were slightly above 0.05 are also given.